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| Name | Class |
|---|---|
| Coordenação de Aperfeiçoamento de Pessoal de NÃvel Superior. | OTHER_GOV |
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The purpose of this study is to determine whether periodontal treatment improves the periodontal clinical parameters in the periodontal patients with diabetes regarding non-diabetics: two years follow-up.
All the subjects in the study will receive non surgical periodontal treatment in one session (full-mouth scaling and root planing). Clinical parameters will be assessed in all teeth (except third molars) by one experienced and trained examiner before treatment and every 3 months for 2 years. Visible plaque index (VPI) will be represented a mean percentage of sites with visible plaque calculated for all teeth analyzed (four sites per tooth). Others parameters will be assessed at six sites per tooth using a manual periodontal probe (15mm). Bleeding on probing (BOP) will be represented the mean percentage of sites with bleeding (up to 15 seconds after probing) calculated for all teeth analyzed. Probing depth (PD - distance between the gingival margin and the bottom of the sulcus/pocket), gingival recession (GR - distance between the cementoenamel junction and gingival margin) and clinical attachment level (CAL - distance between the cementoenamel junction and the bottom of the sulcus/pocket) will be represented a mean distance calculated per site for all teeth analyzed. For blood parameters, an outside laboratory will perform all blood analysis. It will be requested for each subject with diabetes (DG) at baseline, each 3 months post-treatment. Fasting plasma glucose (FPG) will be expressed in milligrams per deciliter and HbA1c will be expressed as a percentage. Statistical analysis will be performed using an available software program and the patient will be considered as the unit of analysis.The data will be processed and analyzed by descriptive and inferential statistics, probably nonparametric.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Diabetic group | Experimental | Subjects with Chronic Periodontitis and Type 2 Diabetes Mellitus treated with non surgical periodontal therapy (Full Mouth Scaling and Root Planing) |
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| Nondiabetic group | Experimental | Subjects with Chronic Periodontitis and without Type 2 Diabetes Mellitus treated with non surgical periodontal therapy (Full Mouth Scaling and Root Planing) |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Full Mouth Scaling and Root Planing | Procedure | This procedure was performed as described by Quirynen et al. 2005 with some modifications |
|
| Measure | Description | Time Frame |
|---|---|---|
| Percentage of bleeding on probing | The mean percentage of periodontal sites with bleeding on probing | Baseline |
| Percentage of bleeding on probing | The mean percentage of periodontal sites with bleeding on probing | at three months |
| Percentage of bleeding on probing | The mean percentage of periodontal sites with bleeding on probing | at six months |
| Percentage of bleeding on probing | The mean percentage of periodontal sites with bleeding on probing | at nine months |
| Percentage of bleeding on probing | The mean percentage of periodontal sites with bleeding on probing | at twelve months |
| Percentage of bleeding on probing | The mean percentage of periodontal sites with bleeding on probing | at eighteen months |
| Percentage of bleeding on probing | The mean percentage of periodontal sites with bleeding on probing | at twenty four months |
| Measure | Description | Time Frame |
|---|---|---|
| Percentage of visible plaque index | The mean percentage of periodontal sites with visible plaque | Baseline and at three, six, nine, twelve, eighteen and twenty four months |
| Probing depth (mm) | The mean of probing depth in millimeters calculated for periodontal sites. |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Bruno CV Gurgel, Doctor | Contact | +558432154136 | bcgurgel@yahoo.com.br | |
| Eduardo A Figueira, Doctor | Contact | +5584999521370 | edufigueira@yahoo.com.br |
| Name | Affiliation | Role |
|---|---|---|
| Bruno CV Gurgel, Doctor | Universidade Federal do Rio Grande do Norte | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Departamento de Odontologia; Universidade Federal do Rio Grande do Norte | Recruiting | Natal | Rio Grande do Norte | 59056-000 | Brazil |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 7560400 | Background | Quirynen M, Bollen CM, Vandekerckhove BN, Dekeyser C, Papaioannou W, Eyssen H. Full- vs. partial-mouth disinfection in the treatment of periodontal infections: short-term clinical and microbiological observations. J Dent Res. 1995 Aug;74(8):1459-67. doi: 10.1177/00220345950740080501. | |
| 12211502 | Background | Lopez NJ, Smith PC, Gutierrez J. Periodontal therapy may reduce the risk of preterm low birth weight in women with periodontal disease: a randomized controlled trial. J Periodontol. 2002 Aug;73(8):911-24. doi: 10.1902/jop.2002.73.8.911. |
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| ID | Term |
|---|---|
| D055113 | Chronic Periodontitis |
| D003924 | Diabetes Mellitus, Type 2 |
| ID | Term |
|---|---|
| D010518 | Periodontitis |
| D010510 | Periodontal Diseases |
| D009059 | Mouth Diseases |
| D009057 | Stomatognathic Diseases |
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| ID | Term |
|---|---|
| D016745 | Root Planing |
| ID | Term |
|---|---|
| D012534 | Dental Scaling |
| D003777 | Dental Prophylaxis |
| D010517 | Periodontics |
| D003813 | Dentistry |
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| Baseline and at three, six, nine, twelve, eighteen and twenty four months |
| Clinical attachment level (mm) | The mean of clinical attachment level in millimeters calculated for periodontal sites. | Baseline and at three, six, nine, twelve, eighteen and twenty four months |
| 31102044 | Derived | Almeida ML, Duarte PM, Figueira EA, Lemos JC, Nobre CMG, Miranda TS, de Vasconcelos Gurgel BC. Effects of a full-mouth disinfection protocol on the treatment of type-2 diabetic and non-diabetic subjects with mild-to-moderate periodontitis: one-year clinical outcomes. Clin Oral Investig. 2020 Jan;24(1):333-341. doi: 10.1007/s00784-019-02927-8. Epub 2019 May 17. |
| D002908 |
| Chronic Disease |
| D020969 | Disease Attributes |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D003920 | Diabetes Mellitus |
| D044882 | Glucose Metabolism Disorders |
| D008659 | Metabolic Diseases |
| D009750 | Nutritional and Metabolic Diseases |
| D004700 | Endocrine System Diseases |
| D013357 |
| Subgingival Curettage |
| D011313 | Preventive Dentistry |