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Patients will be randomized to one of two groups:
The study will be proposed to all patients undergoing formarm or hand surgery under brachial plexus block. Patients will be randomized to one of two groups The first group - supraclavicular group - will receive an ultrasound-guided brachial plexus block via the supraclavicular approach, by injection of 30 ml of a mixture of ropivacaine 0.5 % + mepivacaine 1 %. The second group - retroclavicular group - will receive an ultrasound-guided brachial plexus block via the retroclavicular approach, by injection of 30 ml of a mixture of ropivacaine 0.5 % + mepivacaine 1 %. Primary outcome is success rate at 30 minutes after the injection defined as loss of sensation to pinprick in the forearm and hand. Secondary outcomes are: needling time, time to first analgesic request, postoperative opioid consumption, pain scores at 12 and 24 hours postoperatively, block-related complications, and patient satisfaction.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| supraclavicular | Active Comparator | patients receive a supraclavicular block for forearm or hand surgery with 30 ml of a mixture of ropivacaine 0.5 % and mepivacaine 1 % |
|
| retroclavicular block | Experimental | patients receive a retroclavicular block for forearm or hand surgery with 30 ml of a mixture of ropivacaine 0.5 % and mepivacaine 1 % |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| retroclavicular block | Procedure | retroclavicular block for forearm or hand surgery |
|
| Measure | Description | Time Frame |
|---|---|---|
| Success rate (loss of sensation to pinprick in the forearm and hand) | 30 minutes after the injection |
| Measure | Description | Time Frame |
|---|---|---|
| Needling time in seconds | 15 min | |
| Time to first analgesic request | 24 hours | |
| Block-related complications |
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Inclusion Criteria:
Exclusion Criteria:
History of allergic reaction to local anaesthetics
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| Name | Affiliation | Role |
|---|---|---|
| Sina Grape, MD | Hopital du Valais | Principal Investigator |
| Eric Albrecht, MD | CHUV | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Hopital du Valais | Sion | 1950 | Switzerland |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 30857608 | Derived | Grape S, Pawa A, Weber E, Albrecht E. Retroclavicular vs supraclavicular brachial plexus block for distal upper limb surgery: a randomised, controlled, single-blinded trial. Br J Anaesth. 2019 Apr;122(4):518-524. doi: 10.1016/j.bja.2018.12.022. Epub 2019 Jan 31. |
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| ID | Term |
|---|---|
| D006230 | Hand Injuries |
| ID | Term |
|---|---|
| D014947 | Wounds and Injuries |
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| supraclavicular block | Procedure | supraclavicular block for forearm or hand surgery |
|
| 24 hours |
| Postoperative opioid consumption on postoperative day 1 | 24 hours |
| Pain scores at 12 hours postoperatively | measured on a visual analogue scale between 0 and 100 | 12 hours |
| Pain scores on postoperative day 1 | measured on a visual analogue scale between 0 and 100 | 24 hours |
| Patient satisfaction as assessed by numerical rating scale | Patient satisfaction on a scale between 0 (= completely dissatisfied) and 10 (= completely satisfied) | 24 hours |