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Lack of study staff
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The purpose of this pilot study is to determine whether transcranial direct current stimulation safely and effectively improves symptoms of ADHD.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| DC-Stimulator (PLUS version) | Experimental | For tDCS stimulation, anodal stimulation of the right dorsolateral prefrontal cortex will be performed for twenty minutes at 2mA. The current will be applied by a battery-driven tDCS stimulator via a pair of saline-soaked sponge electrodes (25 cm2 surface). The anodal electrode will be placed on the scalp at the F4 position according to the international 10-20 EEG coordinate system. 20 minute tDCS sessions will be conducted ten times over a two week period |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| DC-Stimulator (PLUS version) | Device | transcranial direct current stimulation |
|
| Measure | Description | Time Frame |
|---|---|---|
| Adult ADHD Investigator Symptom Rating Scale (AISRS) | Each of the individual DSM-V symptoms of ADHD is rated 0 to 3 on a scale of severity. | Baseline to 2 weeks |
| Behavior Rating Inventory of Executive Function-Adult (BRIEF-A) | Assesses levels of executive function deficits | Baseline to 2 weeks |
| Cambridge Neuropsychological Test Automated Battery (CANTAB) | A computer-based system designed to assess executive functioning | Baseline to 2 weeks |
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Inclusion Criteria:
Exclusion Criteria:
- Current or past history of mental retardation, severe sensory impairment such as deafness or blindness, hypomania, mania, psychosis, suicidal or homicidal behavior.
Current moderate to severe symptoms of a mental health condition other than ADHD, assessed using a clinical evaluation and the Adult Self Report Scale that, in the judgment of the investigator, may jeopardize subject safety or interfere with their ability to participate in the study. Specifically, this will include current clinical diagnosis of moderate to severe major depression, or a score on the depressive problem subscale of the ASRS that falls in the clinically significant range.
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| Name | Affiliation | Role |
|---|---|---|
| Craig Surman, MD | Massachusetts General Hospital | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Massachusetts General Hospital | Boston | Massachusetts | 02114 | United States |
| Type | Date | Date Unknown |
|---|---|---|
| Release | Apr 6, 2022 | |
| Reset | Aug 30, 2022 | |
| Release | Mar 14, 2023 | |
| Reset | Dec 7, 2023 | |
| Release | Jan 30, 2024 | |
| Reset | Jul 17, 2024 |
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| Release Date | Unrelease Date | Unrelease Date Unknown | Reset Date | MCP Release Number |
|---|---|---|---|---|
| Apr 6, 2022 | Aug 30, 2022 | |||
| Mar 14, 2023 |
| ID | Term |
|---|---|
| D001289 | Attention Deficit Disorder with Hyperactivity |
| ID | Term |
|---|---|
| D019958 | Attention Deficit and Disruptive Behavior Disorders |
| D065886 | Neurodevelopmental Disorders |
| D001523 | Mental Disorders |
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| Dec 7, 2023 |
| Jan 30, 2024 | Jul 17, 2024 |