Linear mixed model analysis, including participants with a measurement at baseline and/or 12 months, comparing the average 12-month Modified Borg Scale score between control and intervention groups. Our analysis controlled for smoking and before/during the COVID-19 pandemic with fixed effects, while random effects were used for multiple measurement on individuals and study sites.

Difference in average Modified Borg Scale score at 12 months between control and intervention groups.

Standard errors estimated using Kenward-Rogers adjustment for the denominator degrees of freedom.

Linear mixed model analysis, including participants with a measurement at baseline and/or 12 months, comparing the average 12-month body weight between control and intervention groups. Our analysis controlled for smoking and before/during the COVID-19 pandemic with fixed effects, while random effects were used for multiple measurement on individuals and study sites.

Difference in average body weight at 12 months between control and intervention groups.

Standard errors estimated using Kenward-Rogers adjustment for the denominator degrees of freedom.

Linear mixed model analysis, including participants with a measurement at baseline and/or 12 months, comparing the average 12-month SF-12 PCS between control and intervention groups. Our analysis controlled for smoking and before/during the COVID-19 pandemic with fixed effects, while random effects were used for multiple measurement on individuals and study sites.

Difference in average SF-12 PCS at 12 months between control and intervention groups.

Standard errors estimated using Kenward-Rogers adjustment for the denominator degrees of freedom.

Linear mixed model analysis, including participants with a measurement at baseline and/or 12 months, comparing the average 12-month SF-12 MCS between control and intervention groups. Our analysis controlled for smoking and before/during the COVID-19 pandemic with fixed effects, while random effects were used for multiple measurement on individuals and study sites.

Difference in average SF-12 MCS at 12 months between control and intervention groups.

Standard errors estimated using Kenward-Rogers adjustment for the denominator degrees of freedom.

Linear mixed model analysis, including participants with a measurement at baseline and/or 12 months, comparing the average 12-month Framingham Risk Score between control and intervention groups. Our analysis controlled for smoking and before/during the COVID-19 pandemic with fixed effects, while random effects were used for multiple measurement on individuals and study sites.

Difference in average Framingham Risk Score at 12 months between control and intervention groups.

Linear mixed model analysis, including participants with a measurement at baseline and/or 12 months, comparing the average 12 month waist circumference between control and intervention groups. Our analysis controlled for smoking and before/during the COVID-19 pandemic with fixed effects, while random effects were used for multiple measurement on individuals and study sites.

Difference in average waist circumference at 12 months between control and intervention groups.

Standard errors estimated using Kenward-Rogers adjustment for the denominator degrees of freedom.

Linear mixed model analysis, including participants with a measurement at baseline and/or 12 months, comparing the average 12-month systolic blood pressure between control and intervention groups. Our analysis controlled for smoking and before/during the COVID-19 pandemic with fixed effects, while random effects were used for multiple measurement on individuals and study sites.

Difference in average 12 month systolic blood at 12 months between control and intervention groups

Standard errors estimated using Kenward-Rogers adjustment for the denominator degrees of freedom.

Linear mixed model analysis, including participants with a measurement at baseline and/or 12 months, comparing the average 12-month BMI between control and intervention groups. Our analysis controlled for smoking and before/during the COVID-19 pandemic with fixed effects, while random effects were used for multiple measurement on individuals and study sites.

Difference in average BMI at 12 months between control and intervention groups.

Standard errors estimated using Kenward-Rogers adjustment for the denominator degrees of freedom.

Linear mixed model analysis, including participants with a measurement at baseline and/or 12 months, comparing the average 12 month SGRQ-C Symptom score between control and intervention groups. Our analysis controlled for smoking and before/during the COVID-19 pandemic with fixed effects, while random effects were used for multiple measurement on individuals and study sites.

Difference in average SGRQ-C Symptom score at 12 months between control and intervention groups.

Standard errors estimated using Kenward-Rogers adjustment for the denominator degrees of freedom.

Linear mixed model analysis, including participants with a measurement at baseline and/or 12 months, comparing the average 12 month SGRQ-C Activity score between control and intervention groups. Our analysis controlled for smoking and before/during the COVID-19 pandemic with fixed effects, while random effects were used for multiple measurement on individuals and study sites.

Difference in average SGRQ-C Activity score at 12 months between control and intervention groups.

Standard errors estimated using Kenward-Rogers adjustment for the denominator degrees of freedom.

Linear mixed model analysis, including participants with a measurement at baseline and/or 12 months, comparing the average 12 month SGRQ-C Impact score between control and intervention groups. Our analysis controlled for smoking and before/during the COVID-19 pandemic with fixed effects, while random effects were used for multiple measurement on individuals and study sites.

Difference in average SGRQ-C Impact score at 12 months between control and intervention groups.

Standard errors estimated using Kenward-Rogers adjustment for the denominator degrees of freedom.

Linear mixed model analysis, including participants with a measurement at baseline and/or 12 months, comparing the average 12-month SGRQ-C Total score between control and intervention groups. Our analysis controlled for smoking and before/during the COVID-19 pandemic with fixed effects, while random effects were used for multiple measurement on individuals and study sites.

Difference in average SGRQ-C Total score at 12 months between control and intervention groups.

Standard errors estimated using Kenward-Rogers adjustment for the denominator degrees of freedom.