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The study is to determine the long-term outcome of patients with coronary triple vessels disease (TVD) in the real world of China, by three different treatment strategies: percutaneous coronary intervention (PCI), Coronary artery bypass graft (CABG) or optimal medication therapy (OMT).
About 10,000 participants will be enrolled into this retrospective study. Study coordinators will include both men and women over the age of 18 who had angiographic proved triple-vessel disease in a 15 years long-term. Detailed procedural data will be obtained by the study coordinator and local principal investigator. These data will be entered into the electronic data capture system. Participants will have telephone follow-up interviews conducted by the centralized follow-up center at Fuwai Hospital.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Percutaneous coronary intervention | Patients with triple-vessel coronary artery disease underwent percutaneous coronary intervention. | ||
| Coronary artery bypass graft | Patients with triple-vessel coronary artery disease underwent coronary artery bypass graft. | ||
| Optimal medication therapy | Patients with triple-vessel coronary artery disease underwent optimal medication therapy only. |
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| Measure | Description | Time Frame |
|---|---|---|
| All-cause mortality | The mortality due to any cause | Through study completion, an average of 5 year |
| Measure | Description | Time Frame |
|---|---|---|
| Major adverse cardiac and cerebrovascular event | The incidence rate of major adverse cardiac and cerebrovascular event (MACCE), which is a combination of all-cause death, myocardial infarction, stroke and repeat revascularization | Through study completion, an average of 5 year |
| Myocardial infarction |
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Inclusion Criteria:
Exclusion Criteria:
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Between April 2004 and April 2018 in Fuwai Hospital, Beijing, China, consecutive patients with angiography confirmed triple-vessel coronary disease.
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Lei Song, MD | Contact | +86-13910968125 | drsongfw@gmail.com | |
| Lei Song, MD | Contact | +86-13810532620 | lsongqd@yahoo.com |
| Name | Affiliation | Role |
|---|---|---|
| Lei Song, MD | Chinese Academy of Medical Sciences, Fuwai Hospital | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Fuwai Hospital | Recruiting | Beijing | Beijing Municipality | 100037 | China |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 29271373 | Derived | Xu JJ, Zhang Y, Jiang L, Tian J, Song L, Gao Z, Feng XX, Zhao XY, Zhao YY, Wang D, Sun K, Xu LJ, Liu R, Gao RL, Xu B, Song L, Yuan JQ. Comparison of Long-term Outcomes in Patients with Premature Triple-vessel Coronary Disease Undergoing Three Different Treatment Strategies: A Prospective Cohort Study. Chin Med J (Engl). 2018 Jan 5;131(1):1-9. doi: 10.4103/0366-6999.221273. |
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| ID | Term |
|---|---|
| D003324 | Coronary Artery Disease |
| D023921 | Coronary Stenosis |
| D017202 | Myocardial Ischemia |
| ID | Term |
|---|---|
| D003327 | Coronary Disease |
| D006331 | Heart Diseases |
| D002318 | Cardiovascular Diseases |
| D001161 | Arteriosclerosis |
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The Incidence rate of myocardial infarction, including ST elevation myocardial infarction and non-ST elevation myocardial infarction |
| Through study completion, an average of 5 year |
| Stroke | The incidence rate of stroke, including cerebral infarction and hemorrhage | Through study completion, an average of 5 year |
| Repeat revascularization | The incidence rate of repeat revascularization, including target vessel revascularization and non-target vessel revascularization | Through study completion, an average of 5 year |
| D001157 |
| Arterial Occlusive Diseases |
| D014652 | Vascular Diseases |