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Kidney transplantation remains one of the most common organ transplanted today but the surgical technique has changed very little from the original pelvic operation. The deceased donor renal transplant poses a particular challenge to the surgeon due to lack of detailed pre operative vascular assessment. The hemopatch is a promising new sealing synthetic hemostatIc agent with a novel dual mechanism of action that is more convenient to apply rather then using other hemostatic agents, which require warming and/or mixing.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Hemopatch | Experimental | The hemopatch is a promising new sealing synthetic hemostatic agent with a noval dual mechanism of action. The hemopatch is a polyethylene glycol coated (PEG coated) collagen patch. The PEG coating helps in rapid adhesion to the tissue surface while the collagen layer causes platelet activation and adhesion. |
|
| Standard technique | Active Comparator | Standard hemostatic agents (floseal, tisseal). |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Hemopatch | Device |
| ||
| No Hemopatch |
| Measure | Description | Time Frame |
|---|---|---|
| Blood Loss | Blood loss will be measured in ml (cc). | Baseline (Intraoperatively) |
| Measure | Description | Time Frame |
|---|---|---|
| Hemostasis achievement | Hemostasis achievement will be measured in minutes. | Baseline (Intraoperatively) |
| Drop in Hemoglobin | Hemoglobin will be measured in g/L (drop measured from pre-operative levels to post-operative 48 hours). |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Anil Kapoor, MD, FRCSC | McMaster University | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Marylrose Gundayao | Hamilton | Ontario | L8N4A6 | Canada |
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| ID | Term |
|---|---|
| D051437 | Renal Insufficiency |
| ID | Term |
|---|---|
| D007674 | Kidney Diseases |
| D014570 | Urologic Diseases |
| D052776 | Female Urogenital Diseases |
| D005261 | Female Urogenital Diseases and Pregnancy Complications |
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|
| up to 48 hours postoperatively |
| Amount of Perigraft Collection | measured in ml (with ultrasound done within 48 hours of surgery). | up to 48 hours postoperative |
| D000091642 | Urogenital Diseases |
| D052801 | Male Urogenital Diseases |