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The general hypothesis put forward in this study is that the degree of cohesion (agreement) in the relationship, or dyadic adjustment affects a patient's quality of life and clinical course during the first few critical months following diagnosis and the introduction of treatment. The level of cohesion in the relationship is certainly not the only parameter associated with changes in the quality of life. Other factors must also be investigated such as level of education, circumstances surrounding the diagnosis (new diagnosis or relapse), management (single therapy or adjuvant therapy), the level of physical activity, the patient's age and the presence of functional disorders, etc.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Prostate cancer patients |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Gonadotropin-releasing Hormone (GnRH) agonist therapy | Drug | This is a non-interventional study. Thus, investigators are free to choose GnRH agonist therapy product, and modalities of administration in accordance with local Summary of Product Characteristics. |
| Measure | Description | Time Frame |
|---|---|---|
| Change in quality of life of the patient. | Assessment of the dyadic adjustment and its impact on the quality of life of the patient through self-questionnaire by the patient and the partner | Baseline and 6 months |
| Measure | Description | Time Frame |
|---|---|---|
| Assessment of representations of illness | Self-questionnaire by the patient and the partner | Baseline |
| Correlations between quality of life specific to prostate cancer, general quality of life and dyadic adjustment. |
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Inclusion Criteria:
Exclusion Criteria:
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Prostate cancer patients and their partners recruited by urologists.
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| Name | Affiliation | Role |
|---|---|---|
| Ipsen Medical Director | Ipsen | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Ipsen Central Contact | Paris | France |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 35475155 | Result | Droupy S, Colson MH, Pello-Leprince-Ringuet N, Perrot V, Descazeaud A. EQUINOXE study: Impact of relational cohesion and sexuality on the quality of life of patients treated with gonadotropin-releasing hormone agonist for prostate cancer. BJUI Compass. 2021 Oct 19;3(1):45-54. doi: 10.1002/bco2.92. eCollection 2022 Jan. |
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Self-questionnaire by the patient only
| 6 months |
| Proportion of couples with a consistency or inconsistency level of dyadic adjustment | 6 months |
| Investigation of factors associated with patient's perception of dyadic adjustment on changes quality of life | Self-questionnaire by the patient and the partner | Baseline and 6 months |
| ID | Term |
|---|---|
| D011471 | Prostatic Neoplasms |
| ID | Term |
|---|---|
| D005834 | Genital Neoplasms, Male |
| D014565 | Urogenital Neoplasms |
| D009371 | Neoplasms by Site |
| D009369 | Neoplasms |
| D005832 | Genital Diseases, Male |
| D000091662 | Genital Diseases |
| D000091642 | Urogenital Diseases |
| D011469 | Prostatic Diseases |
| D052801 | Male Urogenital Diseases |
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| ID | Term |
|---|---|
| D007987 | Gonadotropin-Releasing Hormone |
| ID | Term |
|---|---|
| D010906 | Pituitary Hormone-Releasing Hormones |
| D007028 | Hypothalamic Hormones |
| D036361 | Peptide Hormones |
| D006728 | Hormones |
| D006730 | Hormones, Hormone Substitutes, and Hormone Antagonists |
| D009479 | Neuropeptides |
| D010455 | Peptides |
| D000602 | Amino Acids, Peptides, and Proteins |
| D009842 | Oligopeptides |
| D009419 | Nerve Tissue Proteins |
| D011506 | Proteins |
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