Optimizing the Delineation of the Tumour Bed in Breast Irradiation | NCT02626858 | Trialant
CompletedInterventionalNot ApplicableUpdated Dec 10, 2015
Optimizing the Delineation of the Tumour Bed in Breast Irradiation
Optimizing the Delineation of the Tumour Bed in Breast Irradiation
ClinicalTrials.gov ID
NCT02626858
Lead Sponsor
Universitaire Ziekenhuizen KU LeuvenOTHER
Overall Status
Completed
Study Type
Interventional
Phase
Not Applicable
Enrollment
25Actual
Last Update Posted
Dec 10, 2015Estimated
Start Date
Feb 2012
Primary Completion Date
Dec 2013Actual
Completion Date
Jul 2015Actual
Official Title
Optimizing the Delineation of the Tumour Bed in Breast Irradiation
Brief Summary
The aim of the present study is:
to verify whether the delineation of the tumour bed, based on the combination of the visible postoperative changes and the position of the surgical clips on a CT scan in treatment position acquired 1 week before the start of the radiotherapy (RT), provides an accurate localisation of the boost volume compared to the localisation of the tumour on a pre-operative CT-scan.
to document the changes that occur in the tumour bed as seen on a CT scan as a function of the delay between surgery and radiotherapy.
to determine the ideal number and the positioning of the clips needed to reproduce the best treatment volume for the boost.
to propose new guidelines for tumour bed definition and delineation based on the study findings.
Detailed Description
Start of the study: february 2012
Breast Cancer
extra treatment planning CT-scan
Ages Eligible for Study
Child (0-17)Adult (18-64)Older Adult (65+)
Sexes Eligible for Study
Female
Accepts Healthy Volunteers
No
Eligibility Criteria
Inclusion Criteria:
Breast Cancer patients, without metastases, who will undergo breast conserving surgery and probably will receive adjuvant chemotherapy and thereafter radiotherapy.