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| Name | Class |
|---|---|
| Pamukkale University | OTHER |
| Manisa Celal Bayar University | OTHER |
| Kocatepe University | OTHER |
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Mechanical low back pain is one most important emergency department presentations of patients seeking pain relief. Although parenteral pain killers such as opioids, non-steroidal anti-inflamatuar drugs and paracetamol are used commonly in these patients, application of analgesics in gel forms might be an reasonable alternative to these drugs with fewer adverse effects.
Mechanical low back pain is one most important emergency department presentations of patients seeking pain relief. Parenteral pain killers such as opioids, non-steroidal anti-inflamatuar drugs (NSAID) and paracetamol are used commonly in these patients. However, these drugs are not out of adverse effects and can not be used in some patients with diverse comorbidities. Gel forms of NSAIDs are used commonly in the outpatient clinics and shown to be effective in these patients by a Cochrane meta-analysis. However, there is no data on the effect of gel forms of analgesics in ED. The application of analgesics in gel forms might be a reasonable alternative to the paranteral drugs with fewer adverse effects.
The present study aimed to reveal the effect of ketoprofen gel in patients presented with low back pain to emergency department.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Ketoprofen | Experimental | Interventional arm: ketoprofen gel 2.5% ketoprofen gel (Fastjel) has been administer as 2 gr in 5 cm area. |
|
| Placebo | Placebo Comparator | Placebo arm: placebo gel form of ketoprofen |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Fastjel | Drug | 2.5% ketoprofen gel (Fastjel) has been administer as 2 gr in 5 cm area. |
|
| Measure | Description | Time Frame |
|---|---|---|
| visual analogue scale at 30 minutes | 30 minutes |
| Measure | Description | Time Frame |
|---|---|---|
| Adverse effects | 30 minutes |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Mustafa Serinken, Professor | Contact | aserinken@hotmail.com | ||
| aysel ozkan | Contact | karek@pau.edu.tr |
| Name | Affiliation | Role |
|---|---|---|
| Mustafa Serinken, Professor | Pamukkale University | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Pamukkale University | Recruiting | Denizli | Turkey (Türkiye) |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 26501533 | Background | Friedman BW, Dym AA, Davitt M, Holden L, Solorzano C, Esses D, Bijur PE, Gallagher EJ. Naproxen With Cyclobenzaprine, Oxycodone/Acetaminophen, or Placebo for Treating Acute Low Back Pain: A Randomized Clinical Trial. JAMA. 2015 Oct 20;314(15):1572-80. doi: 10.1001/jama.2015.13043. |
| Label | URL |
|---|---|
| Pubmed link | View source |
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| ID | Term |
|---|---|
| D017116 | Low Back Pain |
| D004630 | Emergencies |
| ID | Term |
|---|---|
| D001416 | Back Pain |
| D010146 | Pain |
| D009461 | Neurologic Manifestations |
| D012816 | Signs and Symptoms |
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| D013568 |
| Pathological Conditions, Signs and Symptoms |
| D020969 | Disease Attributes |
| D010335 | Pathologic Processes |