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The aim of this study is to collect preliminary data on the effectiveness of acupuncture for the treatment of CIPN in breast cancer patients.
Ideally 10 patients experiencing peripheral neuropathy due to chemotherapy from breast cancer treatment will be included in this study.They will receive 16 total acupuncture treatments over 10 weeks including various points based off of research and classical text and scalp acupuncture.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Acupuncture | Experimental | Acupuncture including scalp needling will be applied to selected points based on literature |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Acupuncture | Device | Acupuncture twice a week for 6 weeks then one treatment a week for 4 weeks. Total 16 treatments in 10 weeks. |
|
| Measure | Description | Time Frame |
|---|---|---|
| Changes in perceived neuropathy as measured by EORTC CIPN-20 | This is a 20-item self-report multidimensional CIPN specific scale that measures sensory, motor and autonomic symptoms of a 1-4 Likert scale. | At baseline, week 6 (treatment 12) and at week 10 (treatment 16) |
| Measure | Description | Time Frame |
|---|---|---|
| Changes in perceived neuropathy as measured by Functional Assessment of Cancer Therapy/Gynecologic Oncology Group-Neurotoxicity (FACT-GOG) Questionnaire | At baseline, week 6 (treatment 12) and at week 10 (treatment 16) | |
| Changes in perceived neuropathy as measured by Visual Analogue Scale of Pain |
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Inclusion criteria:
Minimum of 18 years of age
Currently receiving neurotoxic chemotherapy
Experiencing symptoms of chemotherapy induced neuropathy for at least 1 month
Have a minimum score of 3 on the VAS should have a grade II CIPN on NCICTC
Willing to sign an informed consent
Stable treatment for more than two months before screening
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Sivarama Vinjamury, MD, MAOM | Southern California University of Health Sciences, College of Eastern Medicine | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Southern California University of Health Sciences | Whittier | California | 90604 | United States |
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| ID | Term |
|---|---|
| D012678 | Sensation Disorders |
| D001943 | Breast Neoplasms |
| ID | Term |
|---|---|
| D009461 | Neurologic Manifestations |
| D009422 | Nervous System Diseases |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |
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| ID | Term |
|---|---|
| D015670 | Acupuncture Therapy |
| ID | Term |
|---|---|
| D000529 | Complementary Therapies |
| D013812 | Therapeutics |
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| At baseline, week 6 (treatment 12) and at week 10 (treatment 16) |
| Changes in quality of life as measured by EORTC QLQ-30 | At baseline, week 6 (treatment 12) and at week 10 (treatment 16) |
| D009371 | Neoplasms by Site |
| D009369 | Neoplasms |
| D001941 | Breast Diseases |
| D012871 | Skin Diseases |
| D017437 | Skin and Connective Tissue Diseases |