slow accrual related to change in standard-of-care treatment

The purpose of this study is to determine whether radiation therapy decreases tumor size and tumor spread. The investigators will consent subjects that have been diagnosed with mesothelioma and will undergo radiation therapy followed by surgical resection as their standard of care. The investigators will collect data from past and future medical records as well as data regarding their health status for their lifetime by reviewing life status, treatment status and CT scans.

Inclusion Criteria:

• Subject provides informed consent
• Subject is >18 years of age
• Subject is deemed competent for making medical decisions
• Subject is scheduled to undergo radiation followed by extrapleural pneumonectomy.
• Subject is a surgical candidate
• A negative pregnancy test is required in women of child-bearing potential, as standard of care.

Exclusion Criteria:

• Subject is <18 years old.

Patients receiving treatment at the Mayo Clinic Rochester that have been diagnosed with mesothelioma and will undergo radiation therapy followed by surgical resection as their standard of care.