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| ID | Type | Description | Link |
|---|---|---|---|
| 2014-A01371-46 | Other Identifier | ANSM |
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| Name | Class |
|---|---|
| Hospices Civils de Lyon | OTHER |
| URC-CIC Paris Descartes Necker Cochin | OTHER |
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The purpose of this study is to determine the outcomes of severe osteoporotic fractures hospitalized in France, the risk of incident severe fracture at 2 years and 5 years and the risk of mortality over 2 and 5 years.
In France, the burden of osteoporotic fractures has been studied using cross sectional data from the French hospital national database. The availability of fracture liaison service in the main French cities allows the recruitment of a high number of these targeted patients. A large national multicenter, longitudinal, prospective cohort of patients hospitalized for severe osteoporotic fracture, the CROSS cohort ("Cohorte sur les Risques d'une OStéoporose Sévère"), in order to update data on prognosis (refracture, mortality), epidemiology and of severe osteoporotic fractures.
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| Measure | Description | Time Frame |
|---|---|---|
| Number of new severe fracture over 2 years | To assess the incidence of new severe fracture over 2 years in patients hospitalized for a severe fracture | 2 years |
| Measure | Description | Time Frame |
|---|---|---|
| Number of new severe fracture over 5 years | To assess the incidence of new severe fracture over 5 years in patients hospitalized for a severe fracture | 5 years |
| Measure | Description | Time Frame |
|---|---|---|
| Mortality rate | To study the risk of mortality over 2 years | 2 years |
| Mortality rate | To study the risk of mortality over 5 years | 5 years |
Inclusion Criteria:
Exclusion Criteria:
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Men and women hospitalized for severe fragility fractures in response to low-energy trauma
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| Name | Affiliation | Role |
|---|---|---|
| Karine BRIOT, MD, PhD | Assistance Publique - Hôpitaux de Paris | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Hôpital Cochin | Paris | Paris | 75014 | France |
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Whole blood
| Type of severe fracture |
| 3 months after inclusion and each year during 5 years |
| Number of patients who receive antiosteoporotic treatments and/or calcium and/or vitamin D and/or falls prevention | To check the implementation of 2012 French guidelines, including on the basis on number of performed bone densitometry | 3 months after inclusion and each year during 5 years |
| Quality of life assessed by questionnaire Euroqol (EQ5D) and questionnaire (SF-36) | To assess and compare the quality of life between each type of severe fracture | 3 months after inclusion and each year during 5 years |