Kinetics of Plasma Fibrinogen in Cardiac Surgery

Kinetics of Plasma Fibrinogen During Cardiac and Thoracic Aortic Surgery

The study intends to measure fibrinogen plasma levels during the first 24 hrs in cardiac and thoracic surgical patients who undergo surgical procedures using extracorporeal circulation.

Inclusion Criteria:

• Elective patients undergoing coronary artery bypass grafting, aortic valve replacement or thoracic aortic surgery
• Signed written informed consent

Exclusion Criteria:

• Participation in another study
• Language barrier to understand study purposes (e.g. french as a native language)
• Preoperative low level of plasma fibrinogen (< 1.75 g/l)
• Preoperative anemia (Hb < 10g/dl)
• Emergency treatment
• Intake of anticoagulants other than aspirin within 14 days preceding surgery.
• Known coagulation disorder.
• Jehovah's witnesses