The Effect of Phosphorus on Diet Induced Thermogenesis

The aim of the trial is to investigate the effect of ingestion of 75g of glucose (with or without phosphorus) on diet induced thermogenesis (using indirect calorimetry) and appetite (using visual analogue scales) in lean and obese healthy subjects

Inclusion Criteria:

• Healthy
• Sedentary lifestyle
• Stable weight for the past 3 months
• On a balanced diet

Exclusion Criteria:

• Underweight (BMI<18.5) or overweight/obese (BMI≥25)
• age <18 or > 30 years
• Inability to give valid consent
• Presence of a chronic or acute illness.
• Elevated physical activity level (assesses by the physical activity questionnaire)
• Heavy smokers (≥1 pack per day).
• Weight gain or loss of > 3% in the past 3 months
• History of kidney stones