This study will evaluate the safety and efficacy of sofosbuvir (SOF)-based regimens administered as per the approved prescribing information in adults with chronic hepatitis C virus (HCV) infection treated in routine clinical practice in India.

Inclusion Criteria:

• HCV-infected patients living in India
• Treatment with a SOF-based regimen as determined by the patient's treating physician per the approved prescribing information.
• Patients who provide written and signed informed consent prior to initiation of treatment where required.

Exclusion Criteria:

• Concurrent participation in an HCV clinical trial (except trials not testing investigational medicinal products)
• Patients presenting a risk of not being able to be followed (eg, patients planning to move or leave the country in a foreseeable future)

Adults residing in India aged ≥ 18 years, who are infected with HCV, and for whom the treating physicians in the participating clinics have prescribed a SOF-based regimen as per the approved prescribing information.