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The aim of this study is to determine cut-off values for fetal lung volume by VOCAL and pulmonary artery resistance index by pulsed Doppler in fetuses of diabetic mothers, and correlate the results with postnatal respiratory distress of the term neonates.
Research question:
Can the assessment of fetal lung volume by Virtual Organ Computed-aided Analysis (VOCAL) and pulmonary artery resistance index by pulsed Doppler predict neonatal respiratory distress syndrome in term fetuses of diabetic mothers?
Research hypothesis:
The assessment of fetal lung volume by VOCAL and pulmonary artery resistance index by pulsed Doppler can predict neonatal respiratory distress syndrome in term fetuses of diabetic mothers.
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Three-dimensional (3D) ultrasonography | Device | A longitudinal section of fetal chest will be obtained that clearly depicts the lung. A 3D window will be activated . After complete electronic sweep and assurance of absence of fetal or maternal movements to avoid motion artifacts, 3D multi-planar view will be then obtained |
| Measure | Description | Time Frame |
|---|---|---|
| neonatal respiratory distress | Occurrence of neonatal respiratory distress immediately after delivery utilizing APGAR score at birth in numbers | immediately after delivery |
| Measure | Description | Time Frame |
|---|---|---|
| • Neonatal mortality rate | - Follow up for early neonatal mortality rate after Neonatal Intensive Care Unit admission | One week after delivery |
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Inclusion Criteria:
-Diabetic pregnant women 38 weeks gestation admitted for elective termination due to various obstetric indications
Exclusion Criteria:
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This is a prospective observational study which will be carried out at Ain Shams University Maternity Hospital, Obstetrics and Gynecology department, Faculty of Medicine, Ain Shams University, from December 2015 to December 2016.
Diabetic pregnant women 38 weeks gestation admitted for elective termination by Caesarian section due to various obstetric indications
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| Name | Affiliation | Role |
|---|---|---|
| Mohamed Laban, Professor | Ain Shams University | Principal Investigator |
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| ID | Term |
|---|---|
| D012128 | Respiratory Distress Syndrome |
| ID | Term |
|---|---|
| D008171 | Lung Diseases |
| D012140 | Respiratory Tract Diseases |
| D012120 | Respiration Disorders |
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| ID | Term |
|---|---|
| D014463 | Ultrasonography |
| ID | Term |
|---|---|
| D003952 | Diagnostic Imaging |
| D019937 | Diagnostic Techniques and Procedures |
| D003933 | Diagnosis |
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