12-Month Open-Label Extension Study of Intepirdine (RVT-1... | NCT02586909

NCT02586909

Status Module

Oversight Module

Description Module

Design Module

Interventional Study Design

Biospecimen

No data available

No data is available for this block.

Arms/Interventions Module

Label	Type	Description	Intervention Names
RVT-101 35 mg tablets	Experimental	once daily, oral tablets	Drug: RVT-101 35 mg tablets

Name	Type	Description	Arm Group Labels	Other Names
RVT-101 35 mg tablets	Drug	once daily, oral tablets	RVT-101 35 mg tablets

Outcomes Module

Primary Outcomes

Measure	Description	Time Frame
Occurrence of Adverse Events (AEs) and or Reported Changes in Physical Examinations, Vital Signs Measurements, Electrocardiograms (ECGs), Routine Laboratory Assessments	The primary outcome measure is to study the safety of Intepridine (RVT-101) by determining the incidence of AEs, changes in physical examinations, vital signs measurements, ECGs and clinical laboratory assessments	Baseline to 12 months or Early Termination

Eligibility Module

Contacts/Locations Module

Name	Affiliation	Role
Ilise Lombardo, MD	Axovant Sciences, Inc., Vice President, Clinical Research	Study Director

Facility	Status	City	State	ZIP	Country	Contacts
US112		Phoenix	Arizona	85005	United States
US220

IPD Sharing Statement Module

Results Section

Participant Flow Module

ID	Title	Description
FG000	RVT-101 35 mg Tablets	once daily, oral tablets RVT-101 35 mg tablets: once daily, oral tablets

Baseline Characteristics Module

Outcome Measures Module

Adverse Events Module

More Info Module

Document Section

Large Document Module

Uploaded Document Information

Type	Includes Protocol	Includes SAP	Includes ICF	Document Label	Document Date	Document Uploaded Date	Document File Name
Prot_SAP	Yes	Yes	No	Study Protocol and Statistical Analysis Plan	May 12, 2016

Derived Section

Miscellaneous Info Module

Submission Tracking

No data available

No data is available for this block.

Condition Browse Module

Intervention Browse Module

Baseline Measures

Title

Description

Population Description

Parameter Type

Dispersion Type

Unit of Measure

Calculate Percentage

Denominator Units Selected

Denominators

Classes

Age, Categorical

Count of Participants

Participants

Title

Denominators

Categories

Title	Measurements
<=18 years	BG0000
Between 18 and 65 years	BG000158
>=65 years	BG000

Age, Continuous

Mean

Standard Deviation

years

Title

Denominators

Categories

Title	Measurements
	BG00073.1± 7.55

Sex: Female, Male

Count of Participants

Participants

Title

Denominators

Categories

Title	Measurements
Female	BG000676
Male	BG000423

Ethnicity (NIH/OMB)

Count of Participants

Participants

Title

Denominators

Categories

Title	Measurements
Hispanic or Latino	BG000193
Not Hispanic or Latino	BG000897

Race (NIH/OMB)

Count of Participants

Participants

Title

Denominators

Categories

Title	Measurements
American Indian or Alaska Native	BG0000
Asian	BG00044

Region of Enrollment

Number

participants

Title

Denominators

Categories

Argentina

Title	Measurements
	BG000103

Singapore

Title	Measurements
	BG000

Height

Mean

Standard Deviation

Title

Denominators

Categories

Title	Measurements
	BG000163.3± 9.86

Weight

Mean

Standard Deviation

Title

Denominators

Categories

Title	Measurements
	BG00071.08± 14.490

Body Mass Index (BMI)

Mean

Standard Deviation

kg/m^2

Title

Denominators

Categories

Title	Measurements
	BG00026.59± 4.653

Type

Title

Description

Population Description

Reporting Status

Anticipated Posting Date

Parameter Type

Dispersion Type

Unit of Measure

Calculate Percentage

Time Frame

Units Analyzed

Denominator Units Selected

Arm/Group Information

Denominators

Classes

Analyses

Primary

Occurrence of Adverse Events (AEs) and or Reported Changes in Physical Examinations, Vital Signs Measurements, Electrocardiograms (ECGs), Routine Laboratory Assessments

The primary outcome measure is to study the safety of Intepridine (RVT-101) by determining the incidence of AEs, changes in physical examinations, vital signs measurements, ECGs and clinical laboratory assessments

Posted

Count of Participants

Participants

Baseline to 12 months or Early Termination

ID	Title	Description
OG000	RVT-101 35 mg Tablets	once daily, oral tablets RVT-101 35 mg tablets: once daily, oral tablets

Units	Counts
Participants	OG0001099

Title

Denominators

Categories

Title	Measurements
Subjects with at least one on-treatment AE	OG000549
Subjects with no on-Treatment AE	OG000550

Arm/Groups

ID	Title	Description	Deaths (Affected)	Deaths (At Risk)	Serious Events (Affected)	Serious Events (At Risk)	Other Events (Affected)	Other Events (At Risk)
EG000	RVT-101 35 mg Tablets	once daily, oral tablets RVT-101 35 mg tablets: once daily, oral tablets	10	1,099	87	1,099	526	1,099

Serious Adverse Events

Term	Organ System	Assessment Type	Statistical Information
Pneumonia	Infections and infestations	Systematic Assessment	EG0004 affected1,099 at risk
Gastroenteritis	Infections and infestations	Systematic Assessment	EG0003 affected1,099 at risk
Appendicitis perforated	Infections and infestations	Systematic Assessment	EG0002 affected1,099 at risk
Urinary tract infection	Infections and infestations	Systematic Assessment	EG0002 affected1,099 at risk
Urosepsis	Infections and infestations	Systematic Assessment	EG0002 affected1,099 at risk
Bronchitis	Infections and infestations	Systematic Assessment	EG0001 affected1,099 at risk
Cellulitis	Infections and infestations	Systematic Assessment	EG0001 affected1,099 at risk
Diverticulitis	Infections and infestations	Systematic Assessment	EG0001 affected1,099 at risk
Infected skin ulcer	Infections and infestations	Systematic Assessment	EG0001 affected1,099 at risk
Oesophageal candidiasis	Infections and infestations	Systematic Assessment	EG0001 affected1,099 at risk
Pyelonephritis acute	Infections and infestations	Systematic Assessment	EG0001 affected1,099 at risk
Sepsis	Infections and infestations	Systematic Assessment	EG0001 affected1,099 at risk
Fall	Injury, poisoning and procedural complications	Systematic Assessment	EG0005 affected1,099 at risk
Accidental overdose	Injury, poisoning and procedural complications	Systematic Assessment	EG0001 affected1,099 at risk
Cervical vertebral fracture	Injury, poisoning and procedural complications	Systematic Assessment	EG0001 affected1,099 at risk
Contusion	Injury, poisoning and procedural complications	Systematic Assessment	EG0001 affected1,099 at risk
Craniocerebral injury	Injury, poisoning and procedural complications	Systematic Assessment	EG0001 affected1,099 at risk
Hip fracture	Injury, poisoning and procedural complications	Systematic Assessment	EG0001 affected1,099 at risk
Humerus fracture	Injury, poisoning and procedural complications	Systematic Assessment	EG0001 affected1,099 at risk
Joint dislocation	Injury, poisoning and procedural complications	Systematic Assessment	EG0001 affected1,099 at risk
Postoperative delirium	Injury, poisoning and procedural complications	Systematic Assessment	EG0001 affected1,099 at risk
Road traffic accident	Injury, poisoning and procedural complications	Systematic Assessment	EG0001 affected1,099 at risk
Skull fractured base	Injury, poisoning and procedural complications	Systematic Assessment	EG0001 affected1,099 at risk
Spinal fracture	Injury, poisoning and procedural complications	Systematic Assessment	EG0001 affected1,099 at risk
Subdural haematoma	Injury, poisoning and procedural complications	Systematic Assessment	EG0001 affected1,099 at risk
Basal cell carcinoma	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	Systematic Assessment	EG0003 affected1,099 at risk
Adenocarcinoma gastric	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	Systematic Assessment	EG0001 affected1,099 at risk
Breast cancer	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	Systematic Assessment	EG0001 affected1,099 at risk
Breast cancer female	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	Systematic Assessment	EG0001 affected1,099 at risk
Cholangiocarcinoma	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	Systematic Assessment	EG0001 affected1,099 at risk
Chronic lymphocytic leukaemia	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	Systematic Assessment	EG0001 affected1,099 at risk
Colon cancer	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	Systematic Assessment	EG0001 affected1,099 at risk
Lung adenocarcinoma stage I	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	Systematic Assessment	EG0001 affected1,099 at risk
Metastases to liver	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	Systematic Assessment	EG0001 affected1,099 at risk
Metastatic neoplasm	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	Systematic Assessment	EG0001 affected1,099 at risk
Mycosis fungoides	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	Systematic Assessment	EG0001 affected1,099 at risk
Prostate cancer	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	Systematic Assessment	EG0001 affected1,099 at risk
Prostatic adenoma	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	Systematic Assessment	EG0001 affected1,099 at risk
Renal cancer	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	Systematic Assessment	EG0001 affected1,099 at risk
Squamous cell carcinoma	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	Systematic Assessment	EG0001 affected1,099 at risk
Atrial fibrillation	Cardiac disorders	Systematic Assessment	EG0003 affected1,099 at risk
Cardio-respiratory arrest	Cardiac disorders	Systematic Assessment	EG0003 affected1,099 at risk
Coronary artery disease	Cardiac disorders	Systematic Assessment	EG0002 affected1,099 at risk
Sinus node dysfunction	Cardiac disorders	Systematic Assessment	EG0002 affected1,099 at risk
Atrioventricular block complete	Cardiac disorders	Systematic Assessment	EG0001 affected1,099 at risk
Cardiac failure	Cardiac disorders	Systematic Assessment	EG0001 affected1,099 at risk
Heart valve stenosis	Cardiac disorders	Systematic Assessment	EG0001 affected1,099 at risk
Diarrhoea	Gastrointestinal disorders	Systematic Assessment	EG0002 affected1,099 at risk
Gastritis	Gastrointestinal disorders	Systematic Assessment	EG0002 affected1,099 at risk
Gastritis erosive	Gastrointestinal disorders	Systematic Assessment	EG0002 affected1,099 at risk
Constipation	Gastrointestinal disorders	Systematic Assessment	EG0001 affected1,099 at risk
Pancreatic cyst	Gastrointestinal disorders	Systematic Assessment	EG0001 affected1,099 at risk
Vomiting	Gastrointestinal disorders	Systematic Assessment	EG0001 affected1,099 at risk
Cerebral haemorrhage	Nervous system disorders	Systematic Assessment	EG0001 affected1,099 at risk
Cerebrovascular accident	Nervous system disorders	Systematic Assessment	EG0001 affected1,099 at risk
Dementia of the Alzheimer's type, with delirium	Nervous system disorders	Systematic Assessment	EG0001 affected1,099 at risk
Generalised tonic-clonic seizure	Nervous system disorders	Systematic Assessment	EG0001 affected1,099 at risk
Haemorrhagic stroke	Nervous system disorders	Systematic Assessment	EG0001 affected1,099 at risk
Lumbar radiculopathy	Nervous system disorders	Systematic Assessment	EG0001 affected1,099 at risk
Seizure	Nervous system disorders	Systematic Assessment	EG0001 affected1,099 at risk
Syncope	Nervous system disorders	Systematic Assessment	EG0001 affected1,099 at risk
Transient ischaemic attack	Nervous system disorders	Systematic Assessment	EG0001 affected1,099 at risk
Delirium	Psychiatric disorders	Systematic Assessment	EG0002 affected1,099 at risk
Psychotic disorder	Psychiatric disorders	Systematic Assessment	EG0002 affected1,099 at risk
Agitation	Psychiatric disorders	Systematic Assessment	EG0001 affected1,099 at risk
Delusion	Psychiatric disorders	Systematic Assessment	EG0001 affected1,099 at risk
Dehydration	Metabolism and nutrition disorders	Systematic Assessment	EG0005 affected1,099 at risk
Deep vein thrombosis	Vascular disorders	Systematic Assessment	EG0002 affected1,099 at risk
Aortic aneurysm	Vascular disorders	Systematic Assessment	EG0001 affected1,099 at risk
Hypotension	Vascular disorders	Systematic Assessment	EG0001 affected1,099 at risk
Cholelithiasis	Hepatobiliary disorders	Systematic Assessment	EG0003 affected1,099 at risk
Cholecystitis acute	Hepatobiliary disorders	Systematic Assessment	EG0001 affected1,099 at risk
Acute kidney injury	Renal and urinary disorders	Systematic Assessment	EG0001 affected1,099 at risk
Renal failure	Renal and urinary disorders	Systematic Assessment	EG0001 affected1,099 at risk
Urinary retention	Renal and urinary disorders	Systematic Assessment	EG0001 affected1,099 at risk
Anaemia	Blood and lymphatic system disorders	Systematic Assessment	EG0002 affected1,099 at risk
Hypothermia	General disorders	Systematic Assessment	EG0001 affected1,099 at risk
Sudden death	General disorders	Systematic Assessment	EG0001 affected1,099 at risk
Chronic obstructive pulmonary disease	Respiratory, thoracic and mediastinal disorders	Systematic Assessment	EG0002 affected1,099 at risk
Full blood count decreased	Investigations	Systematic Assessment	EG0001 affected1,099 at risk
Arthralgia	Musculoskeletal and connective tissue disorders	Systematic Assessment	EG0001 affected1,099 at risk
Cervix disorder	Reproductive system and breast disorders	Systematic Assessment	EG0001 affected1,099 at risk
Cervix haemorrhage uterine	Reproductive system and breast disorders	Systematic Assessment	EG0001 affected1,099 at risk

Other Adverse Events

Term	Organ System	Assessment Type	Statistical Information
Anaemia	Blood and lymphatic system disorders	Systematic Assessment	EG0009 affected1,099 at risk
Eosinophilia	Blood and lymphatic system disorders	Systematic Assessment	EG0002 affected1,099 at risk
Iron deficiency anaemia	Blood and lymphatic system disorders	Systematic Assessment	EG0002 affected1,099 at risk
Leukocytosis	Blood and lymphatic system disorders	Systematic Assessment	EG0001 affected1,099 at risk
Leukopenia	Blood and lymphatic system disorders	Systematic Assessment	EG0001 affected1,099 at risk
Lymphopenia	Blood and lymphatic system disorders	Systematic Assessment	EG0003 affected1,099 at risk
Neutrophilia	Blood and lymphatic system disorders	Systematic Assessment	EG0002 affected1,099 at risk
Normochromic normocytic anaemia	Blood and lymphatic system disorders	Systematic Assessment	EG0001 affected1,099 at risk
Thrombocytopenia	Blood and lymphatic system disorders	Systematic Assessment	EG0003 affected1,099 at risk
Atrial flutter	Cardiac disorders	Systematic Assessment	EG0001 affected1,099 at risk
Atrioventricular block first degree	Cardiac disorders	Systematic Assessment	EG0004 affected1,099 at risk
Bradycardia	Cardiac disorders	Systematic Assessment	EG0002 affected1,099 at risk
Cardiac failure congestive	Cardiac disorders	Systematic Assessment	EG0001 affected1,099 at risk
Mitral valve incompetence	Cardiac disorders	Systematic Assessment	EG0001 affected1,099 at risk
Myocardial ischaemia	Cardiac disorders	Systematic Assessment	EG0003 affected1,099 at risk
Palpitations	Cardiac disorders	Systematic Assessment	EG0003 affected1,099 at risk
Sinus arrhythmia	Cardiac disorders	Systematic Assessment	EG0001 affected1,099 at risk
Ventricular extrasystoles	Cardiac disorders	Systematic Assessment	EG0002 affected1,099 at risk
Cerumen impaction	Ear and labyrinth disorders	Systematic Assessment	EG0001 affected1,099 at risk
Motion sickness	Ear and labyrinth disorders	Systematic Assessment	EG0001 affected1,099 at risk
Vertigo	Ear and labyrinth disorders	Systematic Assessment	EG0007 affected1,099 at risk
Hypothyroidism	Endocrine disorders	Systematic Assessment	EG0003 affected1,099 at risk
Thyroid mass	Endocrine disorders	Systematic Assessment	EG0001 affected1,099 at risk
Angle closure glaucoma	Eye disorders	Systematic Assessment	EG0001 affected1,099 at risk
Blepharitis	Eye disorders	Systematic Assessment	EG0001 affected1,099 at risk
Cataract	Eye disorders	Systematic Assessment	EG0008 affected1,099 at risk
Dry eye	Eye disorders	Systematic Assessment	EG0001 affected1,099 at risk
Macular degeneration	Eye disorders	Systematic Assessment	EG0001 affected1,099 at risk
Ocular hyperaemia	Eye disorders	Systematic Assessment	EG0001 affected1,099 at risk
Ocular rosacea	Eye disorders	Systematic Assessment	EG0001 affected1,099 at risk
Retinal detachment	Eye disorders	Systematic Assessment	EG0001 affected1,099 at risk
Abdominal discomfort	Gastrointestinal disorders	Systematic Assessment	EG0001 affected1,099 at risk
Abdominal distension	Gastrointestinal disorders	Systematic Assessment	EG0001 affected1,099 at risk
Abdominal mass	Gastrointestinal disorders	Systematic Assessment	EG0001 affected1,099 at risk
Abdominal pain	Gastrointestinal disorders	Systematic Assessment	EG0004 affected1,099 at risk
Anal fissure	Gastrointestinal disorders	Systematic Assessment	EG0001 affected1,099 at risk
Colitis ischaemic	Gastrointestinal disorders	Systematic Assessment	EG0001 affected1,099 at risk
Constipation	Gastrointestinal disorders	Systematic Assessment	EG0005 affected1,099 at risk
Dental caries	Gastrointestinal disorders	Systematic Assessment	EG0001 affected1,099 at risk
Diarrhoea	Gastrointestinal disorders	Systematic Assessment	EG00017 affected1,099 at risk
Dry mouth	Gastrointestinal disorders	Systematic Assessment	EG0002 affected1,099 at risk
Dyspepsia	Gastrointestinal disorders	Systematic Assessment	EG0003 affected1,099 at risk
Faeces soft	Gastrointestinal disorders	Systematic Assessment	EG0001 affected1,099 at risk
Gastric ulcer	Gastrointestinal disorders	Systematic Assessment	EG0001 affected1,099 at risk
Gastritis	Gastrointestinal disorders	Systematic Assessment	EG0001 affected1,099 at risk
Gastrooesophageal reflux disease	Gastrointestinal disorders	Systematic Assessment	EG0002 affected1,099 at risk
Haematochezia	Gastrointestinal disorders	Systematic Assessment	EG0001 affected1,099 at risk
Haemorrhoids	Gastrointestinal disorders	Systematic Assessment	EG0003 affected1,099 at risk
Hiatus hernia	Gastrointestinal disorders	Systematic Assessment	EG0001 affected1,099 at risk
Nausea	Gastrointestinal disorders	Systematic Assessment	EG00015 affected1,099 at risk
Oral contusion	Gastrointestinal disorders	Systematic Assessment	EG0001 affected1,099 at risk
Salivary hypersecretion	Gastrointestinal disorders	Systematic Assessment	EG0001 affected1,099 at risk
Toothache	Gastrointestinal disorders	Systematic Assessment	EG0003 affected1,099 at risk
Umbilical hernia	Gastrointestinal disorders	Systematic Assessment	EG0002 affected1,099 at risk
Vomiting	Gastrointestinal disorders	Systematic Assessment	EG00013 affected1,099 at risk
Asthenia	General disorders	Systematic Assessment	EG0001 affected1,099 at risk
Catheter site haemorrhage	General disorders	Systematic Assessment	EG0001 affected1,099 at risk
Chest pain	General disorders	Systematic Assessment	EG0002 affected1,099 at risk
Facial pain	General disorders	Systematic Assessment	EG0001 affected1,099 at risk
Fat necrosis	General disorders	Systematic Assessment	EG0001 affected1,099 at risk
Fatigue	General disorders	Systematic Assessment	EG0004 affected1,099 at risk
Feeling cold	General disorders	Systematic Assessment	EG0001 affected1,099 at risk
Gait disturbance	General disorders	Systematic Assessment	EG0006 affected1,099 at risk
Gravitational oedema	General disorders	Systematic Assessment	EG0001 affected1,099 at risk
Hyperthermia	General disorders	Systematic Assessment	EG0001 affected1,099 at risk
Influenza like illness	General disorders	Systematic Assessment	EG0002 affected1,099 at risk
Non-cardiac chest pain	General disorders	Systematic Assessment	EG0003 affected1,099 at risk
Oedema peripheral	General disorders	Systematic Assessment	EG0008 affected1,099 at risk
Pyrexia	General disorders	Systematic Assessment	EG0001 affected1,099 at risk
Thirst	General disorders	Systematic Assessment	EG0001 affected1,099 at risk
Cholecystitis	Hepatobiliary disorders	Systematic Assessment	EG0001 affected1,099 at risk
Cholelithiasis	Hepatobiliary disorders	Systematic Assessment	EG0001 affected1,099 at risk
Hepatic steatosis	Hepatobiliary disorders	Systematic Assessment	EG0001 affected1,099 at risk
Seasonal allergy	Immune system disorders	Systematic Assessment	EG0003 affected1,099 at risk
Bacteriuria	Infections and infestations	Systematic Assessment	EG0001 affected1,099 at risk
Bronchitis	Infections and infestations	Systematic Assessment	EG00012 affected1,099 at risk
Bronchitis bacterial	Infections and infestations	Systematic Assessment	EG0001 affected1,099 at risk
Cellulitis	Infections and infestations	Systematic Assessment	EG0001 affected1,099 at risk
Conjunctivitis bacterial	Infections and infestations	Systematic Assessment	EG0001 affected1,099 at risk
Cystitis	Infections and infestations	Systematic Assessment	EG0001 affected1,099 at risk
Fungal skin infection	Infections and infestations	Systematic Assessment	EG0001 affected1,099 at risk
Gastroenteritis	Infections and infestations	Systematic Assessment	EG0006 affected1,099 at risk
Gastroenteritis viral	Infections and infestations	Systematic Assessment	EG0001 affected1,099 at risk
Helicobacter infection	Infections and infestations	Systematic Assessment	EG0001 affected1,099 at risk
Herpes zoster	Infections and infestations	Systematic Assessment	EG0003 affected1,099 at risk
Hordeolum	Infections and infestations	Systematic Assessment	EG0001 affected1,099 at risk
Infected bite	Infections and infestations	Systematic Assessment	EG0001 affected1,099 at risk
Infected dermal cyst	Infections and infestations	Systematic Assessment	EG0001 affected1,099 at risk
Influenza	Infections and infestations	Systematic Assessment	EG0007 affected1,099 at risk
Laryngitis	Infections and infestations	Systematic Assessment	EG0001 affected1,099 at risk
Localised infection	Infections and infestations	Systematic Assessment	EG0001 affected1,099 at risk
Lower respiratory tract infection	Infections and infestations	Systematic Assessment	EG0006 affected1,099 at risk
Lyme disease	Infections and infestations	Systematic Assessment	EG0002 affected1,099 at risk
Nasopharyngitis	Infections and infestations	Systematic Assessment	EG00023 affected1,099 at risk
Onychomycosis	Infections and infestations	Systematic Assessment	EG0002 affected1,099 at risk
Oral candidiasis	Infections and infestations	Systematic Assessment	EG0001 affected1,099 at risk
Oral herpes	Infections and infestations	Systematic Assessment	EG0001 affected1,099 at risk
Otitis media	Infections and infestations	Systematic Assessment	EG0001 affected1,099 at risk
Paronychia	Infections and infestations	Systematic Assessment	EG0002 affected1,099 at risk
Pharyngitis	Infections and infestations	Systematic Assessment	EG0001 affected1,099 at risk
Pharyngitis streptococcal	Infections and infestations	Systematic Assessment	EG0001 affected1,099 at risk
Pneumonia	Infections and infestations	Systematic Assessment	EG0003 affected1,099 at risk
Postoperative wound infection	Infections and infestations	Systematic Assessment	EG0001 affected1,099 at risk
Pyuria	Infections and infestations	Systematic Assessment	EG0001 affected1,099 at risk
Respiratory tract infection	Infections and infestations	Systematic Assessment	EG0001 affected1,099 at risk
Root canal infection	Infections and infestations	Systematic Assessment	EG0001 affected1,099 at risk
Sinusitis	Infections and infestations	Systematic Assessment	EG0002 affected1,099 at risk
Tooth abscess	Infections and infestations	Systematic Assessment	EG0001 affected1,099 at risk
Tooth infection	Infections and infestations	Systematic Assessment	EG0002 affected1,099 at risk
Upper respiratory tract infection	Infections and infestations	Systematic Assessment	EG00018 affected1,099 at risk
Urinary tract infection	Infections and infestations	Systematic Assessment	EG00045 affected1,099 at risk
Urinary tract infection bacterial	Infections and infestations	Systematic Assessment	EG0001 affected1,099 at risk
Viral infection	Infections and infestations	Systematic Assessment	EG0001 affected1,099 at risk
Viral upper respiratory tract infection	Infections and infestations	Systematic Assessment	EG0001 affected1,099 at risk
Wound infection	Infections and infestations	Systematic Assessment	EG0001 affected1,099 at risk
Ankle fracture	Injury, poisoning and procedural complications	Systematic Assessment	EG0002 affected1,099 at risk
Arthropod bite	Injury, poisoning and procedural complications	Systematic Assessment	EG0002 affected1,099 at risk
Asbestosis	Injury, poisoning and procedural complications	Systematic Assessment	EG0001 affected1,099 at risk
Concussion	Injury, poisoning and procedural complications	Systematic Assessment	EG0001 affected1,099 at risk
Confusion postoperative	Injury, poisoning and procedural complications	Systematic Assessment	EG0001 affected1,099 at risk
Contusion	Injury, poisoning and procedural complications	Systematic Assessment	EG00010 affected1,099 at risk
Craniocerebral injury	Injury, poisoning and procedural complications	Systematic Assessment	EG0001 affected1,099 at risk
Dose calculation error	Injury, poisoning and procedural complications	Systematic Assessment	EG0001 affected1,099 at risk
Excoriation	Injury, poisoning and procedural complications	Systematic Assessment	EG0001 affected1,099 at risk
Face injury	Injury, poisoning and procedural complications	Systematic Assessment	EG0001 affected1,099 at risk
Fall	Injury, poisoning and procedural complications	Systematic Assessment	EG00051 affected1,099 at risk
Forearm fracture	Injury, poisoning and procedural complications	Systematic Assessment	EG0001 affected1,099 at risk
Frostbite	Injury, poisoning and procedural complications	Systematic Assessment	EG0001 affected1,099 at risk
Hand fracture	Injury, poisoning and procedural complications	Systematic Assessment	EG0003 affected1,099 at risk
Head injury	Injury, poisoning and procedural complications	Systematic Assessment	EG0005 affected1,099 at risk
Heat stroke	Injury, poisoning and procedural complications	Systematic Assessment	EG0001 affected1,099 at risk
Humerus fracture	Injury, poisoning and procedural complications	Systematic Assessment	EG0002 affected1,099 at risk
Joint dislocation	Injury, poisoning and procedural complications	Systematic Assessment	EG0001 affected1,099 at risk
Laceration	Injury, poisoning and procedural complications	Systematic Assessment	EG0002 affected1,099 at risk
Ligament sprain	Injury, poisoning and procedural complications	Systematic Assessment	EG0001 affected1,099 at risk
Limb injury	Injury, poisoning and procedural complications	Systematic Assessment	EG0002 affected1,099 at risk
Lumbar vertebral fracture	Injury, poisoning and procedural complications	Systematic Assessment	EG0001 affected1,099 at risk
Post-traumatic neck syndrome	Injury, poisoning and procedural complications	Systematic Assessment	EG0001 affected1,099 at risk
Procedural pain	Injury, poisoning and procedural complications	Systematic Assessment	EG0002 affected1,099 at risk
Radius fracture	Injury, poisoning and procedural complications	Systematic Assessment	EG0002 affected1,099 at risk
Rib fracture	Injury, poisoning and procedural complications	Systematic Assessment	EG0002 affected1,099 at risk
Road traffic accident	Injury, poisoning and procedural complications	Systematic Assessment	EG0002 affected1,099 at risk
Skin abrasion	Injury, poisoning and procedural complications	Systematic Assessment	EG0006 affected1,099 at risk
Skin injury	Injury, poisoning and procedural complications	Systematic Assessment	EG0001 affected1,099 at risk
Skin wound	Injury, poisoning and procedural complications	Systematic Assessment	EG0001 affected1,099 at risk
Spinal fracture	Injury, poisoning and procedural complications	Systematic Assessment	EG0002 affected1,099 at risk
Splinter	Injury, poisoning and procedural complications	Systematic Assessment	EG0001 affected1,099 at risk
Sunburn	Injury, poisoning and procedural complications	Systematic Assessment	EG0001 affected1,099 at risk
Tendon rupture	Injury, poisoning and procedural complications	Systematic Assessment	EG0001 affected1,099 at risk
Thermal burn	Injury, poisoning and procedural complications	Systematic Assessment	EG0001 affected1,099 at risk
Tooth fracture	Injury, poisoning and procedural complications	Systematic Assessment	EG0003 affected1,099 at risk
Ulna fracture	Injury, poisoning and procedural complications	Systematic Assessment	EG0001 affected1,099 at risk
Upper limb fracture	Injury, poisoning and procedural complications	Systematic Assessment	EG0001 affected1,099 at risk
Wound	Injury, poisoning and procedural complications	Systematic Assessment	EG0002 affected1,099 at risk
Wound secretion	Injury, poisoning and procedural complications	Systematic Assessment	EG0001 affected1,099 at risk
Wrist fracture	Injury, poisoning and procedural complications	Systematic Assessment	EG0002 affected1,099 at risk
Alanine aminotransferase increased	Investigations	Systematic Assessment	EG0008 affected1,099 at risk
Aspartate aminotransferase increased	Investigations	Systematic Assessment	EG0005 affected1,099 at risk
Blood alkaline phosphatase increased	Investigations	Systematic Assessment	EG0009 affected1,099 at risk
Blood bilirubin increased	Investigations	Systematic Assessment	EG0001 affected1,099 at risk
Blood cholesterol increased	Investigations	Systematic Assessment	EG0001 affected1,099 at risk
Blood creatinine decreased	Investigations	Systematic Assessment	EG0002 affected1,099 at risk
Blood creatinine increased	Investigations	Systematic Assessment	EG0006 affected1,099 at risk
Blood electrolytes abnormal	Investigations	Systematic Assessment	EG0001 affected1,099 at risk
Blood glucose increased	Investigations	Systematic Assessment	EG0001 affected1,099 at risk
Blood potassium increased	Investigations	Systematic Assessment	EG0002 affected1,099 at risk
Blood pressure increased	Investigations	Systematic Assessment	EG0004 affected1,099 at risk
Blood urea increased	Investigations	Systematic Assessment	EG0003 affected1,099 at risk
Blood urine present	Investigations	Systematic Assessment	EG0002 affected1,099 at risk
Creatinine renal clearance decreased	Investigations	Systematic Assessment	EG00015 affected1,099 at risk
Crystal urine	Investigations	Systematic Assessment	EG0001 affected1,099 at risk
Crystal urine present	Investigations	Systematic Assessment	EG0002 affected1,099 at risk
Electrocardiogram QT prolonged	Investigations	Systematic Assessment	EG0002 affected1,099 at risk
Eosinophil count increased	Investigations	Systematic Assessment	EG0001 affected1,099 at risk
Gamma-glutamyltransferase increased	Investigations	Systematic Assessment	EG00014 affected1,099 at risk
Glomerular filtration rate decreased	Investigations	Systematic Assessment	EG0001 affected1,099 at risk
Haemoglobin decreased	Investigations	Systematic Assessment	EG0001 affected1,099 at risk
Hepatic enzyme increased	Investigations	Systematic Assessment	EG0001 affected1,099 at risk
Liver function test increased	Investigations	Systematic Assessment	EG0003 affected1,099 at risk
Lymphocyte count decreased	Investigations	Systematic Assessment	EG0008 affected1,099 at risk
Mammogram abnormal	Investigations	Systematic Assessment	EG0001 affected1,099 at risk
Monocyte count increased	Investigations	Systematic Assessment	EG0001 affected1,099 at risk
Neutrophil count decreased	Investigations	Systematic Assessment	EG0001 affected1,099 at risk
Neutrophil count increased	Investigations	Systematic Assessment	EG0003 affected1,099 at risk
Platelet count decreased	Investigations	Systematic Assessment	EG0001 affected1,099 at risk
Protein urine present	Investigations	Systematic Assessment	EG0001 affected1,099 at risk
Red blood cell count increased	Investigations	Systematic Assessment	EG0001 affected1,099 at risk
Red blood cells urine	Investigations	Systematic Assessment	EG0001 affected1,099 at risk
Transaminases increased	Investigations	Systematic Assessment	EG0001 affected1,099 at risk
Urine analysis abnormal	Investigations	Systematic Assessment	EG0004 affected1,099 at risk
Urine leukocyte esterase	Investigations	Systematic Assessment	EG0001 affected1,099 at risk
Weight decreased	Investigations	Systematic Assessment	EG0007 affected1,099 at risk
Weight increased	Investigations	Systematic Assessment	EG0005 affected1,099 at risk
White blood cell count increased	Investigations	Systematic Assessment	EG0001 affected1,099 at risk
Decreased appetite	Metabolism and nutrition disorders	Systematic Assessment	EG0008 affected1,099 at risk
Dehydration	Metabolism and nutrition disorders	Systematic Assessment	EG0005 affected1,099 at risk
Diabetes mellitus	Metabolism and nutrition disorders	Systematic Assessment	EG0002 affected1,099 at risk
Diabetes mellitus inadequate control	Metabolism and nutrition disorders	Systematic Assessment	EG0001 affected1,099 at risk
Diabetic metabolic decompensation	Metabolism and nutrition disorders	Systematic Assessment	EG0001 affected1,099 at risk
Food craving	Metabolism and nutrition disorders	Systematic Assessment	EG0001 affected1,099 at risk
Gout	Metabolism and nutrition disorders	Systematic Assessment	EG0001 affected1,099 at risk
Hypercalcaemia	Metabolism and nutrition disorders	Systematic Assessment	EG0001 affected1,099 at risk
Hypercholesterolaemia	Metabolism and nutrition disorders	Systematic Assessment	EG0002 affected1,099 at risk
Hyperglycaemia	Metabolism and nutrition disorders	Systematic Assessment	EG0002 affected1,099 at risk
Hyperkalaemia	Metabolism and nutrition disorders	Systematic Assessment	EG0009 affected1,099 at risk
Hypocalcaemia	Metabolism and nutrition disorders	Systematic Assessment	EG0001 affected1,099 at risk
Hypoglycaemia	Metabolism and nutrition disorders	Systematic Assessment	EG0001 affected1,099 at risk
Hypokalaemia	Metabolism and nutrition disorders	Systematic Assessment	EG0001 affected1,099 at risk
Hyponatraemia	Metabolism and nutrition disorders	Systematic Assessment	EG0002 affected1,099 at risk
Increased appetite	Metabolism and nutrition disorders	Systematic Assessment	EG0002 affected1,099 at risk
Type 2 diabetes mellitus	Metabolism and nutrition disorders	Systematic Assessment	EG0001 affected1,099 at risk
Underweight	Metabolism and nutrition disorders	Systematic Assessment	EG0001 affected1,099 at risk
Vitamin B12 deficiency	Metabolism and nutrition disorders	Systematic Assessment	EG0001 affected1,099 at risk
Vitamin D deficiency	Metabolism and nutrition disorders	Systematic Assessment	EG0002 affected1,099 at risk
Arthralgia	Musculoskeletal and connective tissue disorders	Systematic Assessment	EG00010 affected1,099 at risk
Arthritis	Musculoskeletal and connective tissue disorders	Systematic Assessment	EG0001 affected1,099 at risk
Back pain	Musculoskeletal and connective tissue disorders	Systematic Assessment	EG00022 affected1,099 at risk
Bursitis	Musculoskeletal and connective tissue disorders	Systematic Assessment	EG0001 affected1,099 at risk
Extremity contracture	Musculoskeletal and connective tissue disorders	Systematic Assessment	EG0001 affected1,099 at risk
Intervertebral disc protrusion	Musculoskeletal and connective tissue disorders	Systematic Assessment	EG0001 affected1,099 at risk
Intervertebral disc space narrowing	Musculoskeletal and connective tissue disorders	Systematic Assessment	EG0001 affected1,099 at risk
Joint stiffness	Musculoskeletal and connective tissue disorders	Systematic Assessment	EG0001 affected1,099 at risk
Joint swelling	Musculoskeletal and connective tissue disorders	Systematic Assessment	EG0001 affected1,099 at risk
Muscle rigidity	Musculoskeletal and connective tissue disorders	Systematic Assessment	EG0001 affected1,099 at risk
Muscle spasms	Musculoskeletal and connective tissue disorders	Systematic Assessment	EG0002 affected1,099 at risk
Musculoskeletal pain	Musculoskeletal and connective tissue disorders	Systematic Assessment	EG0006 affected1,099 at risk
Musculoskeletal stiffness	Musculoskeletal and connective tissue disorders	Systematic Assessment	EG0002 affected1,099 at risk
Myalgia	Musculoskeletal and connective tissue disorders	Systematic Assessment	EG0002 affected1,099 at risk
Neck pain	Musculoskeletal and connective tissue disorders	Systematic Assessment	EG0003 affected1,099 at risk
Osteoarthritis	Musculoskeletal and connective tissue disorders	Systematic Assessment	EG0004 affected1,099 at risk
Osteoporosis	Musculoskeletal and connective tissue disorders	Systematic Assessment	EG0001 affected1,099 at risk
Pain in extremity	Musculoskeletal and connective tissue disorders	Systematic Assessment	EG0007 affected1,099 at risk
Plantar fasciitis	Musculoskeletal and connective tissue disorders	Systematic Assessment	EG0001 affected1,099 at risk
Rheumatoid arthritis	Musculoskeletal and connective tissue disorders	Systematic Assessment	EG0001 affected1,099 at risk
Rotator cuff syndrome	Musculoskeletal and connective tissue disorders	Systematic Assessment	EG0003 affected1,099 at risk
Sacroiliitis	Musculoskeletal and connective tissue disorders	Systematic Assessment	EG0001 affected1,099 at risk
Spinal osteoarthritis	Musculoskeletal and connective tissue disorders	Systematic Assessment	EG0001 affected1,099 at risk
Spinal pain	Musculoskeletal and connective tissue disorders	Systematic Assessment	EG0003 affected1,099 at risk
Tendonitis	Musculoskeletal and connective tissue disorders	Systematic Assessment	EG0002 affected1,099 at risk
Angiolipoma	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	Systematic Assessment	EG0001 affected1,099 at risk
Basal cell carcinoma	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	Systematic Assessment	EG0001 affected1,099 at risk
Fibroma	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	Systematic Assessment	EG0001 affected1,099 at risk
Pyogenic granuloma	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	Systematic Assessment	EG0001 affected1,099 at risk
Squamous cell carcinoma	Neoplasms benign, malignant and unspecified (incl cysts and polyps)	Systematic Assessment	EG0001 affected1,099 at risk
Apraxia	Nervous system disorders	Systematic Assessment	EG0001 affected1,099 at risk
Areflexia	Nervous system disorders	Systematic Assessment	EG0001 affected1,099 at risk
Balance disorder	Nervous system disorders	Systematic Assessment	EG0001 affected1,099 at risk
Bradykinesia	Nervous system disorders	Systematic Assessment	EG0001 affected1,099 at risk
Carpal tunnel syndrome	Nervous system disorders	Systematic Assessment	EG0002 affected1,099 at risk
Cervicobrachial syndrome	Nervous system disorders	Systematic Assessment	EG0001 affected1,099 at risk
Cognitive disorder	Nervous system disorders	Systematic Assessment	EG0004 affected1,099 at risk
Decreased vibratory sense	Nervous system disorders	Systematic Assessment	EG0003 affected1,099 at risk
Dementia Alzheimer's type	Nervous system disorders	Systematic Assessment	EG0005 affected1,099 at risk
Dizziness	Nervous system disorders	Systematic Assessment	EG00017 affected1,099 at risk
Dizziness postural	Nervous system disorders	Systematic Assessment	EG0001 affected1,099 at risk
Dysaesthesia	Nervous system disorders	Systematic Assessment	EG0001 affected1,099 at risk
Dysgeusia	Nervous system disorders	Systematic Assessment	EG0001 affected1,099 at risk
Dyspraxia	Nervous system disorders	Systematic Assessment	EG0001 affected1,099 at risk
Epilepsy	Nervous system disorders	Systematic Assessment	EG0002 affected1,099 at risk
Facial paralysis	Nervous system disorders	Systematic Assessment	EG0001 affected1,099 at risk
Gait apraxia	Nervous system disorders	Systematic Assessment	EG0001 affected1,099 at risk
Headache	Nervous system disorders	Systematic Assessment	EG00017 affected1,099 at risk
Hypertonia	Nervous system disorders	Systematic Assessment	EG0001 affected1,099 at risk
Lethargy	Nervous system disorders	Systematic Assessment	EG0001 affected1,099 at risk
Loss of consciousness	Nervous system disorders	Systematic Assessment	EG0001 affected1,099 at risk
Memory impairment	Nervous system disorders	Systematic Assessment	EG0001 affected1,099 at risk
Myoclonus	Nervous system disorders	Systematic Assessment	EG0001 affected1,099 at risk
Paraesthesia	Nervous system disorders	Systematic Assessment	EG0001 affected1,099 at risk
Parkinsonian gait	Nervous system disorders	Systematic Assessment	EG0001 affected1,099 at risk
Parkinsonism	Nervous system disorders	Systematic Assessment	EG0003 affected1,099 at risk
Postural tremor	Nervous system disorders	Systematic Assessment	EG0001 affected1,099 at risk
Presyncope	Nervous system disorders	Systematic Assessment	EG0001 affected1,099 at risk
Psychomotor hyperactivity	Nervous system disorders	Systematic Assessment	EG0001 affected1,099 at risk
Somnolence	Nervous system disorders	Systematic Assessment	EG0002 affected1,099 at risk
Syncope	Nervous system disorders	Systematic Assessment	EG0006 affected1,099 at risk
Tension headache	Nervous system disorders	Systematic Assessment	EG0001 affected1,099 at risk
Transient ischaemic attack	Nervous system disorders	Systematic Assessment	EG0002 affected1,099 at risk
Tremor	Nervous system disorders	Systematic Assessment	EG0004 affected1,099 at risk
Abnormal behaviour	Psychiatric disorders	Systematic Assessment	EG0005 affected1,099 at risk
Abnormal dreams	Psychiatric disorders	Systematic Assessment	EG0002 affected1,099 at risk
Adjustment disorder with mixed anxiety and depressed mood	Psychiatric disorders	Systematic Assessment	EG0001 affected1,099 at risk
Aggression	Psychiatric disorders	Systematic Assessment	EG0008 affected1,099 at risk
Agitation	Psychiatric disorders	Systematic Assessment	EG00017 affected1,099 at risk
Anxiety	Psychiatric disorders	Systematic Assessment	EG00016 affected1,099 at risk
Confusional state	Psychiatric disorders	Systematic Assessment	EG0007 affected1,099 at risk
Delirium	Psychiatric disorders	Systematic Assessment	EG0001 affected1,099 at risk
Delusion	Psychiatric disorders	Systematic Assessment	EG0007 affected1,099 at risk
Depressed mood	Psychiatric disorders	Systematic Assessment	EG0005 affected1,099 at risk
Depression	Psychiatric disorders	Systematic Assessment	EG00014 affected1,099 at risk
Disorientation	Psychiatric disorders	Systematic Assessment	EG0003 affected1,099 at risk
Dysphemia	Psychiatric disorders	Systematic Assessment	EG0001 affected1,099 at risk
Encopresis	Psychiatric disorders	Systematic Assessment	EG0001 affected1,099 at risk
Enuresis	Psychiatric disorders	Systematic Assessment	EG0001 affected1,099 at risk
Frustration tolerance decreased	Psychiatric disorders	Systematic Assessment	EG0002 affected1,099 at risk
Hallucination	Psychiatric disorders	Systematic Assessment	EG0004 affected1,099 at risk
Hallucination, olfactory	Psychiatric disorders	Systematic Assessment	EG0001 affected1,099 at risk
Hallucination, visual	Psychiatric disorders	Systematic Assessment	EG0006 affected1,099 at risk
Insomnia	Psychiatric disorders	Systematic Assessment	EG0008 affected1,099 at risk
Irritability	Psychiatric disorders	Systematic Assessment	EG00011 affected1,099 at risk
Libido decreased	Psychiatric disorders	Systematic Assessment	EG0001 affected1,099 at risk
Mental status changes	Psychiatric disorders	Systematic Assessment	EG0001 affected1,099 at risk
Mood altered	Psychiatric disorders	Systematic Assessment	EG0002 affected1,099 at risk
Mood swings	Psychiatric disorders	Systematic Assessment	EG0001 affected1,099 at risk
Nervousness	Psychiatric disorders	Systematic Assessment	EG0001 affected1,099 at risk
Neuropsychiatric symptoms	Psychiatric disorders	Systematic Assessment	EG0001 affected1,099 at risk
Nightmare	Psychiatric disorders	Systematic Assessment	EG0001 affected1,099 at risk
Panic attack	Psychiatric disorders	Systematic Assessment	EG0002 affected1,099 at risk
Paranoia	Psychiatric disorders	Systematic Assessment	EG0002 affected1,099 at risk
Psychotic disorder	Psychiatric disorders	Systematic Assessment	EG0001 affected1,099 at risk
Restlessness	Psychiatric disorders	Systematic Assessment	EG0003 affected1,099 at risk
Sleep disorder	Psychiatric disorders	Systematic Assessment	EG0005 affected1,099 at risk
Suicidal ideation	Psychiatric disorders	Systematic Assessment	EG0005 affected1,099 at risk
Suspiciousness	Psychiatric disorders	Systematic Assessment	EG0001 affected1,099 at risk
Tearfulness	Psychiatric disorders	Systematic Assessment	EG0002 affected1,099 at risk
Calculus bladder	Renal and urinary disorders	Systematic Assessment	EG0001 affected1,099 at risk
Chronic kidney disease	Renal and urinary disorders	Systematic Assessment	EG0002 affected1,099 at risk
Haematuria	Renal and urinary disorders	Systematic Assessment	EG0004 affected1,099 at risk
Hypertonic bladder	Renal and urinary disorders	Systematic Assessment	EG0001 affected1,099 at risk
Nephrolithiasis	Renal and urinary disorders	Systematic Assessment	EG0001 affected1,099 at risk
Pollakiuria	Renal and urinary disorders	Systematic Assessment	EG0004 affected1,099 at risk
Polyuria	Renal and urinary disorders	Systematic Assessment	EG0002 affected1,099 at risk
Renal cyst	Renal and urinary disorders	Systematic Assessment	EG0002 affected1,099 at risk
Renal failure	Renal and urinary disorders	Systematic Assessment	EG0003 affected1,099 at risk
Ureterolithiasis	Renal and urinary disorders	Systematic Assessment	EG0003 affected1,099 at risk
Urethral fistula	Renal and urinary disorders	Systematic Assessment	EG0001 affected1,099 at risk
Urinary incontinence	Renal and urinary disorders	Systematic Assessment	EG00012 affected1,099 at risk
Urinary retention	Renal and urinary disorders	Systematic Assessment	EG0001 affected1,099 at risk
Atrophic vulvovaginitis	Reproductive system and breast disorders	Systematic Assessment	EG0001 affected1,099 at risk
Benign prostatic hyperplasia	Reproductive system and breast disorders	Systematic Assessment	EG0002 affected1,099 at risk
Breast haematoma	Reproductive system and breast disorders	Systematic Assessment	EG0001 affected1,099 at risk
Cervix disorder	Reproductive system and breast disorders	Systematic Assessment	EG0001 affected1,099 at risk
Fibrocystic breast disease	Reproductive system and breast disorders	Systematic Assessment	EG0001 affected1,099 at risk
Prostatomegaly	Reproductive system and breast disorders	Systematic Assessment	EG0001 affected1,099 at risk
Scrotal pain	Reproductive system and breast disorders	Systematic Assessment	EG0001 affected1,099 at risk
Asthma	Respiratory, thoracic and mediastinal disorders	Systematic Assessment	EG0001 affected1,099 at risk
Bronchiectasis	Respiratory, thoracic and mediastinal disorders	Systematic Assessment	EG0001 affected1,099 at risk
Bronchitis chronic	Respiratory, thoracic and mediastinal disorders	Systematic Assessment	EG0001 affected1,099 at risk
Catarrh	Respiratory, thoracic and mediastinal disorders	Systematic Assessment	EG0002 affected1,099 at risk
Chronic obstructive pulmonary disease	Respiratory, thoracic and mediastinal disorders	Systematic Assessment	EG0002 affected1,099 at risk
Cough	Respiratory, thoracic and mediastinal disorders	Systematic Assessment	EG00010 affected1,099 at risk
Dyspnoea	Respiratory, thoracic and mediastinal disorders	Systematic Assessment	EG0004 affected1,099 at risk
Dyspnoea exertional	Respiratory, thoracic and mediastinal disorders	Systematic Assessment	EG0002 affected1,099 at risk
Epistaxis	Respiratory, thoracic and mediastinal disorders	Systematic Assessment	EG0004 affected1,099 at risk
Hiccups	Respiratory, thoracic and mediastinal disorders	Systematic Assessment	EG0001 affected1,099 at risk
Oropharyngeal pain	Respiratory, thoracic and mediastinal disorders	Systematic Assessment	EG0003 affected1,099 at risk
Paranasal sinus hypersecretion	Respiratory, thoracic and mediastinal disorders	Systematic Assessment	EG0001 affected1,099 at risk
Rales	Respiratory, thoracic and mediastinal disorders	Systematic Assessment	EG0002 affected1,099 at risk
Rhinitis allergic	Respiratory, thoracic and mediastinal disorders	Systematic Assessment	EG0001 affected1,099 at risk
Rhinorrhoea	Respiratory, thoracic and mediastinal disorders	Systematic Assessment	EG0001 affected1,099 at risk
Wheezing	Respiratory, thoracic and mediastinal disorders	Systematic Assessment	EG0001 affected1,099 at risk
Alopecia areata	Skin and subcutaneous tissue disorders	Systematic Assessment	EG0001 affected1,099 at risk
Dermatitis	Skin and subcutaneous tissue disorders	Systematic Assessment	EG0003 affected1,099 at risk
Dermatitis allergic	Skin and subcutaneous tissue disorders	Systematic Assessment	EG0001 affected1,099 at risk
Dermatitis contact	Skin and subcutaneous tissue disorders	Systematic Assessment	EG0002 affected1,099 at risk
Eczema	Skin and subcutaneous tissue disorders	Systematic Assessment	EG0002 affected1,099 at risk
Erythema	Skin and subcutaneous tissue disorders	Systematic Assessment	EG0002 affected1,099 at risk
Hair growth abnormal	Skin and subcutaneous tissue disorders	Systematic Assessment	EG0001 affected1,099 at risk
Hyperhidrosis	Skin and subcutaneous tissue disorders	Systematic Assessment	EG0001 affected1,099 at risk
Hyperkeratosis	Skin and subcutaneous tissue disorders	Systematic Assessment	EG0001 affected1,099 at risk
Ingrowing nail	Skin and subcutaneous tissue disorders	Systematic Assessment	EG0002 affected1,099 at risk
Macule	Skin and subcutaneous tissue disorders	Systematic Assessment	EG0001 affected1,099 at risk
Nail discolouration	Skin and subcutaneous tissue disorders	Systematic Assessment	EG0001 affected1,099 at risk
Onychoclasis	Skin and subcutaneous tissue disorders	Systematic Assessment	EG0001 affected1,099 at risk
Photosensitivity reaction	Skin and subcutaneous tissue disorders	Systematic Assessment	EG0001 affected1,099 at risk
Pruritus	Skin and subcutaneous tissue disorders	Systematic Assessment	EG0002 affected1,099 at risk
Rash	Skin and subcutaneous tissue disorders	Systematic Assessment	EG0006 affected1,099 at risk
Rash generalised	Skin and subcutaneous tissue disorders	Systematic Assessment	EG0003 affected1,099 at risk
Skin discolouration	Skin and subcutaneous tissue disorders	Systematic Assessment	EG0001 affected1,099 at risk
Skin hyperpigmentation	Skin and subcutaneous tissue disorders	Systematic Assessment	EG0001 affected1,099 at risk
Skin lesion	Skin and subcutaneous tissue disorders	Systematic Assessment	EG0002 affected1,099 at risk
Skin ulcer	Skin and subcutaneous tissue disorders	Systematic Assessment	EG0005 affected1,099 at risk
Urticaria	Skin and subcutaneous tissue disorders	Systematic Assessment	EG0001 affected1,099 at risk
Arteriosclerosis	Vascular disorders	Systematic Assessment	EG0001 affected1,099 at risk
Blood pressure fluctuation	Vascular disorders	Systematic Assessment	EG0001 affected1,099 at risk
Deep vein thrombosis	Vascular disorders	Systematic Assessment	EG0001 affected1,099 at risk
Flushing	Vascular disorders	Systematic Assessment	EG0001 affected1,099 at risk
Haematoma	Vascular disorders	Systematic Assessment	EG0002 affected1,099 at risk
Hot flush	Vascular disorders	Systematic Assessment	EG0003 affected1,099 at risk
Hypertension	Vascular disorders	Systematic Assessment	EG00010 affected1,099 at risk
Hypotension	Vascular disorders	Systematic Assessment	EG0003 affected1,099 at risk
Orthostatic hypertension	Vascular disorders	Systematic Assessment	EG0001 affected1,099 at risk
Orthostatic hypotension	Vascular disorders	Systematic Assessment	EG0002 affected1,099 at risk
Peripheral vascular disorder	Vascular disorders	Systematic Assessment	EG0001 affected1,099 at risk
Peripheral venous disease	Vascular disorders	Systematic Assessment	EG0001 affected1,099 at risk

Ancestor Terms

ID	Term
D003704	Dementia
D001927	Brain Diseases
D002493	Central Nervous System Diseases
D009422	Nervous System Diseases
D024801	Tauopathies
D019636	Neurodegenerative Diseases
D019965	Neurocognitive Disorders
D001523	Mental Disorders