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The current clinical guidelines for management of atopic dermatitis now recommend bleach baths. This requires simply the addition of regular household bleach to twice-weekly baths. At the Mayo Clinic, dilute acetic acid (vinegar) has been recommended for decades in wet wraps to treat patients hospitalized for their atopic dermatitis. However, this practice has not been widely adopted in the pediatric dermatology community. Will the use of dilute acetic acid (vinegar) in twice weekly baths help manage atopic dermatitis in pediatric patients as well as, or better than, the current accepted guidelines?
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Bleach | Active Comparator | Patients will use bleach added to their baths twice a week. |
|
| Vinegar | Active Comparator | Patients will use vinegar (dilute acetic acid) added to their baths twice a week. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Bathing Additive | Other |
|
| Measure | Description | Time Frame |
|---|---|---|
| EASI score at 6 months | 6 months |
| Measure | Description | Time Frame |
|---|---|---|
| Courses of antibiotics required | 1 year |
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Inclusion Criteria:
Patients from 6 months to 17 years of age
Currently residing in US.
Follow up visits at 1 month, 3 months and 6 months after initiation of treatment in study (Figure 1).
Last follow-up at 1 year in clinic or via written mailed-out survey.
Diagnosis of atopic dermatitis AND
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Megha Tollefson, MD | Mayo Clinic | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Mayo Clinic in Rochester | Rochester | Minnesota | 55905 | United States |
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| ID | Term |
|---|---|
| D003876 | Dermatitis, Atopic |
| ID | Term |
|---|---|
| D012873 | Skin Diseases, Genetic |
| D030342 | Genetic Diseases, Inborn |
| D009358 | Congenital, Hereditary, and Neonatal Diseases and Abnormalities |
| D003872 | Dermatitis |
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| D012871 | Skin Diseases |
| D017437 | Skin and Connective Tissue Diseases |
| D017443 | Skin Diseases, Eczematous |
| D006969 | Hypersensitivity, Immediate |
| D006967 | Hypersensitivity |
| D007154 | Immune System Diseases |