The Effect of Oxycodone to the Placental Circulation at Early Labour

The Effect of Oxycodone to the Placental Circulation at Early Labour

Oxycodone is used to treat pain in early labor, however the effect of oxycodone to placental or fetal circulation has not been evaluated. Oxycodone is increasingly used to treat labor pain in the early phase. The aim of the randomised, double blinded, placebo controlled study was to evaluate the effects of oxycodone in placental circulation, efficacy and safety of oxycodone and the effects to the newborn.

Inclusion Criteria:

• oxycodone planned for pain relief

  • age 18 years or more
  • Informed consent obtained
  • Full term pregnancy

Exclusion Criteria:

• No oxycodone planned

  • age less than 18 years
  • No informed consent
  • not full term pregnancy

• Other contraindication to oxycodone