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| Name | Class |
|---|---|
| KU Leuven | OTHER |
This prospective cohort study aims to determine the incidence of hospitalization-associated disability and its association with risk factors at the patient level and with care and hospital processes. For this, patients aged 70 years or older admitted for elective valve surgery or elective transcatheter aortic valve implantation or as a result of symptomatic moderate to severe valvular heart disease will be consecutively included from 01 October 2015 to 29 February 2016.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Valvular heart disease | All patients aged 70 years or older, consecutively admitted for elective heart valve surgery or if admitted for elective transcatheter aortic valve implantation, or if a patient presents with symptomatic moderate to severe valvular heart disease on hospital admission as evidenced by moderate to severe valve regurgitation or stenosis will be included in this cohort. Participants will be observed up to 30 days post-hospital discharge |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Not applicable (observational design) | Procedure |
|
| Measure | Description | Time Frame |
|---|---|---|
| Hospitalization-associated Disability | The loss of ability to complete one of the basic ADLs independently between baseline and hospital discharge. | Up to 30 days post-hospital discharge |
| Measure | Description | Time Frame |
|---|---|---|
| The six minutes walking distance test | Up to 30 days post-hospital discharge | |
| Five meter gait speed test | Up to 30 days post-hospital discharge | |
| Timed get-up and go test |
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Inclusion Criteria:
Exclusion Criteria:
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Patients aged 70 years and older admitted for elective heart valve surgery (replacement, repair or combined with CABG) or if admitted for elective transcatheter aortic valve implantation, or if a patient presents with symptomatic moderate to severe valvular heart disease on hospital admission.
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| Name | Affiliation | Role |
|---|---|---|
| Mieke Deschodt, PhD | KU Leuven | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Universitaire Ziekenhuizen Leuven | Leuven | Vlaams-Brabant | 3000 | Belgium |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 29301463 | Derived | Jonckers M, Van Grootven B, Willemyns E, Hornikx M, Jeuris A, Dubois C, Herregods MC, Deschodt M. Hospitalization-associated disability in older adults with valvular heart disease: incidence, risk factors and its association with care processes. Acta Cardiol. 2018 Jan 4;73(6):566-572. doi: 10.1080/00015385.2017.1421300. |
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| ID | Term |
|---|---|
| D007049 | Iatrogenic Disease |
| D006349 | Heart Valve Diseases |
| ID | Term |
|---|---|
| D020969 | Disease Attributes |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D006331 | Heart Diseases |
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| Up to 30 days post-hospital discharge |
| Peak extension torque measured at the right side and evaluated at 60° of knee flexion | Isometric quadriceps strength will be measured using a dynamometer (Biodex system 4 pro; Enraf Nonius; Delft, The Netherlands) | Up to 30 days post-hospital discharge |
| Peak handgrip force assessed at the dominant side with the elbow at 90° of flexion, and the forearm and wrist in a neutral position. | Isometric handgrip force will be measured with a hydraulic hand dynamometer (Jamar dynamometer; JA Preston Corporation; Jackson, MI) | Up to 30 days post-hospital discharge |
| Inappropriate medication prescribing | Inappropriate medication prescribing using the RASP-list (Rationalization of Home Medication by an Adjusted STOPP list in Older Patients) | Up to 30 days post-hospital discharge |
| D002318 | Cardiovascular Diseases |