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This prospective randomized controlled trial studies the efficacy and safety of treating influenza with the reconciling exterior and interior therapy. A total of 300 cases of seasonal flu in Beijing is to be collected, and divided into one treatment group and two control groups. Patients in the treatment group will receive Liugan Shuangjie Heji, while patients in control groups will receive Shufeng Jiedu Capsule and Oseltamivir Phosphate Capsule respectively, for a course of 5 days. The study assesses the efficacy and safety of treating influenza with the reconciling therapy based on the following outcome measures: the time it takes from the medicine intake to 0.5℃ drop of body temperature, and the time it takes for the body temperature to return to normal.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Liugan Shuangjie Heji Group | Experimental | Liugan Shuangjie Heji, take orally, 4 times a day, 100 ml each time (i.e. two doses per day), for a course of five days. |
|
| Shufeng Jiedu Capsule Group | Active Comparator | Shufeng Jiedu Capsule, take orally, 3 times a day, 4 capsules each time, for a course of five days. |
|
| Oseltamivir Phosphate Capsule Group | Active Comparator | Oseltamivir Phosphate Capsule, take orally, 2 times a day, 75 mg each time, for a course of five days. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Liugan Shuangjie Heji | Drug |
| ||
| Shufeng Jiedu Capsule |
| Measure | Description | Time Frame |
|---|---|---|
| time from the medicine intake to 0.5℃ drop of body temperature | five days | |
| time for the body temperature to return to normal | five days |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Yang - Jiao, MD | Contact | +86 13601016612 | Yangjiao2013@sina.cn | |
| Zhisong - Wu, MD | Contact | +86 13811578627 | wuzhisong1220@163.com |
| Name | Affiliation | Role |
|---|---|---|
| Yang - Jiao, MD | Dongfang Hospital Beijing University of Chinese Medicine | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Dongfang Hospital affiliated to Beijing University of Chinese Medicine | Recruiting | Beijing | 100078 | China |
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| ID | Term |
|---|---|
| D007251 | Influenza, Human |
| ID | Term |
|---|---|
| D012141 | Respiratory Tract Infections |
| D007239 | Infections |
| D009976 | Orthomyxoviridae Infections |
| D012327 | RNA Virus Infections |
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| ID | Term |
|---|---|
| C000612830 | shufeng jiedu |
| D053139 | Oseltamivir |
| ID | Term |
|---|---|
| D000081 | Acetamides |
| D000577 | Amides |
| D009930 | Organic Chemicals |
| D053138 | Cyclohexenes |
| D003510 |
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| Drug |
|
| Oseltamivir Phosphate Capsule | Drug |
|
| D014777 | Virus Diseases |
| D012140 | Respiratory Tract Diseases |
| Cyclohexanes |
| D003516 | Cycloparaffins |
| D006840 | Hydrocarbons, Alicyclic |
| D006844 | Hydrocarbons, Cyclic |
| D006838 | Hydrocarbons |