This study was designed to determine the role of antibiotics reduction mammaplasty influence surgical site infections rates.

Prevention of SSI is important due to its morbidity, longer hospital stays and higher costs. In many surgical procedures where the risk of infection is relatively low and the postoperative infection can be treated properly, the role of antibiotics is not clear.

Despite the lack of evidence from prospective randomized controlled trials of evaluation, the use of antibiotics in plastic surgery is widespread in order to offer the highest safety standards patients.

The breast reduction is defined as "clean surgery" with a lower infection rate to 3.4%. Thus, the antibiotic is not recommended. However, studies have shown a real rate of infection associated with procedures ranging from 4-36%.

Thus, this trial was designed to verify the role of antibiotics in reduction mammaplasty.

Inclusion Criteria:

• Breast hypertrophy
• Body mass index between 19 to 30 kg/m2

Exclusion Criteria:

• Patients undergoing a surgical procedure in the breast
• Diagnosis of breast pathology
• Smoking
• Childbirth or lactation less than a year
• Uncontrolled comorbidities
• Use of immunosuppressive drugs
• Misuse of capsules supplied
• Absence during the weekly follow-up