Open Label Trial of Utility of Cryobiopsy in the Multidisciplinary Diagnosis of Idiopathic Interstitial Lung Disease

Open Label Trial of Utility of Cryobiopsy in the Multidisciplinary Diagnosis of Idiopathic Interstitial Lung Disease

A multicenter, multinational, prospective study to clarify, whether the addition of cryobiopsy can avoid surgical lung biopsy in a clinically relevant proportion of patients with suspected Idiopathic Interstitial Pneumonia

Inclusion Criteria:

• IIP suspected on clinical and radiologic grounds

Exclusion Criteria:

• Age >80y and <18y
• FVC< 55%, DCO<35%
• Platelet count <100000/µl
• acetylsalicylic acid, clopidogrel or equivalent during the last 5 days
• INR > l,3,
• elevated PTT (> 40 s)
• documented pulmonary hypertension PAPS >50mmHg
• HR-CT highly suspicious for sarcoidosis