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This study evaluates the effects "High Protein Atkin's Complete (lacto) VEgetaRian Diet (Acronym; 'PACER' diet) on weight, body composition and metabolic profiles in obese Asian Indians subjects living in north India.
Increasing the protein consumption promotes weight loss through several mechanisms. Diets high in protein promote energy expenditure through increased postprandial thermogenesis, increase total daily expenditure and increase satiety as compared to carbohydrate. The present study aims to evaluate the effects "High Protein Atkin's Complete (lacto) VEgetaRian Diet (Acronym; 'PACER' diet) on weight, body composition and metabolic profiles in obese Asian Indians subjects living in north India.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| PACER diet | Experimental | High Protein Atkin's Complete (Lacto) VEgetaRian Diet (PACER Diet) to be followed for 8 weeks. |
|
| Standard weight reducing diet | Active Comparator | This group was prescribed Standard weight reducing diet to be followed for 8 weeks. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| PACER Diet | Dietary Supplement | Pacer diet to be followed for 8 weeks |
| |
| Measure | Description | Time Frame |
|---|---|---|
| Weight loss (kg) | 8 weeks |
| Measure | Description | Time Frame |
|---|---|---|
| Lipid profile | 8 weeks | |
| Insulin resistance | 8 weeks |
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Inclusion Criteria
Exclusion Criteria
Body mass index (BMI) > 40 kg/m2
Any patient taking/requiring drugs known to effect insulin resistance, lipids, vascular reactivity, during the intervention period would be excluded from the study
Patients on any drugs that change the weight or in conditions where dietary protein supplementation is contraindicated
Subjects who are consuming a high protein diet on randomization, to be excluded
Acute infections or chronic debilitating diseases like tuberculosis, malignancy, HIV infection etc
Any life threatening serious disorder of the liver, kidneys, heart, lungs or other organs
Pregnancy & lactation
Patients having diagnosed with any of the following:
Unwillingness to give written informed consent for participation in the study
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| Name | Affiliation | Role |
|---|---|---|
| Anoop Misra, MD | Diabetes Foundation, India | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Fortis Flt Lt Rajan Dhall Hospital | New Delhi | National Capital Territory of Delhi | 110070 | India |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 25418400 | Background | Bhardwaj S, Misra A. Obesity, diabetes and the Asian phenotype. World Rev Nutr Diet. 2015;111:116-22. doi: 10.1159/000362308. Epub 2014 Nov 17. No abstract available. | |
| 19506174 | Background | Jenkins DJ, Wong JM, Kendall CW, Esfahani A, Ng VW, Leong TC, Faulkner DA, Vidgen E, Greaves KA, Paul G, Singer W. The effect of a plant-based low-carbohydrate ("Eco-Atkins") diet on body weight and blood lipid concentrations in hyperlipidemic subjects. Arch Intern Med. 2009 Jun 8;169(11):1046-54. doi: 10.1001/archinternmed.2009.115. |
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| ID | Term |
|---|---|
| D009765 | Obesity |
| ID | Term |
|---|---|
| D050177 | Overweight |
| D044343 | Overnutrition |
| D009748 | Nutrition Disorders |
| D009750 | Nutritional and Metabolic Diseases |
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| Standard weight reducing diet |
| Other |
Standard weight reducing diet to be followed for 8 weeks |
|
| D001835 |
| Body Weight |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |