Protexa® Versus TiLoopBra® in Immediate Breast Reconstruction- A Pilot Study

Protexa® Versus TiLoopBra® in Immediate Breast Reconstruction- A Pilot Study

Randomized controlled trial to look at early complications, cosmetic outcome, patient satisfaction and thickness of the tissue overlying the implant at the lower pole in immediate implant based breast reconstruction after Skin or Nipple Sparing Mastectomy with either a mesh (TiLOOP Bra) or an ADM (Protexa). Multicenter austrian trial with four breast cancer centers, 50 patients randomized 1:1 in the TiLoop or Protexa group.

Inclusion Criteria:

• breast cancer patients with indication for skin or nipple sparing mastectomy
• BRCA1/2 mutation carriers with indication for skin or nipple sparing mastectomy

Exclusion Criteria:

• prior local radiotherapy
• inflammatory breast cancer