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| Name | Class |
|---|---|
| VA Office of Research and Development | FED |
The purpose of this study is to conduct a pilot trial investigating cognitive training in older Veterans with a history of traumatic brain injury (TBI) to assess training effects, acceptability of training to participants, and to explore whether other factors influence training effects.
A study of older Veterans (60-85 years old) who have 1) a history of repetitive mild TBI or at least one moderate TBI and 2) subjective cognitive complaints. Participants will be randomized to one of three conditions for 4 weeks: Project:Evolution (EVO) multitask video game, EVO words video game, or an assessment only control condition. Participants will complete assessment visits at baseline, post-intervention (1 month after baseline), and 3 months post-intervention (4 months after baseline).
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| EVO multitask video game | Experimental |
| |
| EVO words video game | Experimental |
| |
| Assessment Only | No Intervention |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| EVO multitask video game | Behavioral | Participants will play a multitasking game for 4 weeks |
|
| Measure | Description | Time Frame |
|---|---|---|
| Acceptability based on participant ratings | Acceptability ratings assessed post-intervention (1-month after baseline) | |
| Participant adherence to game play | Total adherence over the 4 week intervention phase | |
| Change in cognitive functioning based on neurocognitive test battery | Baseline, post-intervention (1-month after baseline), and 3-months post-intervention (4-months after baseline) |
| Measure | Description | Time Frame |
|---|---|---|
| Change in self-reported everyday cognitive functioning [Neuro-QOL (Quality of Life in Neurological Disorders) Cognitive Function inventory] | Baseline, post-intervention (1-month after baseline), and 3-months post-intervention (4-months after baseline) | |
| Change in everyday functioning [University of California San Diego (UCSD) Performance Based Skills Assessment (UPSA)] |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Allison Kaup, PhD | San Francisco Veterans Affairs Medical Center | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| San Francisco VA Medical Center | San Francisco | California | 94121 | United States | ||
| Veterans Home of California |
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| EVO words video game | Behavioral | Participants will play a word puzzle game for 4 weeks |
|
| Baseline, post-intervention (1-month after baseline), and 3-months post-intervention (4-months after baseline) |
| Change in mood symptoms (Geriatric Depression Scale) | Baseline, post-intervention (1-month after baseline), and 3-months post-intervention (4-months after baseline) |
| Change in EVO performance (EVO Monitor) | Baseline, post-intervention (1-month after baseline), and 3-months post-intervention (4-months after baseline) |
| Yountville |
| California |
| 94599 |
| United States |
| ID | Term |
|---|---|
| D000070642 | Brain Injuries, Traumatic |
| ID | Term |
|---|---|
| D001930 | Brain Injuries |
| D001927 | Brain Diseases |
| D002493 | Central Nervous System Diseases |
| D009422 | Nervous System Diseases |
| D006259 | Craniocerebral Trauma |
| D020196 | Trauma, Nervous System |
| D014947 | Wounds and Injuries |
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