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The purpose of this study was to examine the cost effectiveness of critical care in a middle income country with limited resources.
The main study hypothesis was that critical care is cost effective in low resources setting.
The investigators objective was to calculate the cost effectiveness of treatment of critically ill patients in a medical ICU of a middle income country with limited access to ICU resources.
Methods: Consecutive critically ill medical patients treated in a recently established medical ICU in Sarajevo, Bosnia and Herzegovina, were prospectively recorded and a subsequent cost utility analysis of intensive care in comparison to hospital ward treatment from the perspective of health care system was performed. Incremental cost effectiveness was calculated using estimates of ICU versus non-ICU treatment effectiveness based on a formal systematic review of published studies. Decision analytic modeling was used to compare treatment alternatives. Sensitivity analyses of the key model parameters were performed.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| ICU patients | The actual cohort of 148 critically ill medical patients that received the treatment in the intensive care unit (ICU). The interventions include interventions that are usually performed within the ICU such as mechanical ventilation, non-invasive ventilation, neuromuscular blockade, renal replacement therapy. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| mechanical ventilation | Procedure | ventilator support for the patients presenting with acute respiratory failure |
|
| Measure | Description | Time Frame |
|---|---|---|
| survival | mortality was recorded one year after hospital discharge and subtracted from the value od 100% in order to get one year survival | one year after hospital release |
| Measure | Description | Time Frame |
|---|---|---|
| mortality | 30 days and 60 days after critical illness onset and one year after hospital release | |
| health related quality of life (HRQOL) | HRQOL was assessed using EQ5D-3L questionnaire | one year after hospital release |
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Inclusion Criteria:
Exclusion Criteria:
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consecutive critically ill patients treated during one year in a recently established medical ICU at the Sarajevo University Clinical Center.
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| Name | Affiliation | Role |
|---|---|---|
| Hajrunisa Cubro, MD | Medical ICU University of Sarajevo Clinical Center, Sarajevo, Bosnia and Herzegovina | Principal Investigator |
| Ognjen Gajic, MD, MSc | Division of Pulmonary and Critical Care Mayo Clinic Rochester MN USA | Study Chair |
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| ID | Term |
|---|---|
| D016638 | Critical Illness |
| ID | Term |
|---|---|
| D020969 | Disease Attributes |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
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| ID | Term |
|---|---|
| D012121 | Respiration, Artificial |
| D012122 | Ventilators, Mechanical |
| D019148 | Neuromuscular Blockade |
| D017582 | Renal Replacement Therapy |
| D017583 | Hemodiafiltration |
| D063087 | Noninvasive Ventilation |
| D045422 | Continuous Positive Airway Pressure |
| ID | Term |
|---|---|
| D058109 | Airway Management |
| D013812 | Therapeutics |
| D012151 | Resuscitation |
| D004638 | Emergency Treatment |
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| neuromuscular blockade | Procedure | paralysis of the skeletal muscles in order to optimize mechanical ventilation, especially during ARDS |
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| renal replacement therapy | Procedure | the procedures used to treat acute kidney injury |
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| non-invasive ventilation | Procedure | Procedure used for ventilation support in patients with congestive heart failure, pulmonary edema, COPD and some other conditions. |
|
|
| D012138 |
| Respiratory Therapy |
| D004864 | Equipment and Supplies |
| D000760 | Anesthesia and Analgesia |
| D008919 | Investigative Techniques |
| D006435 | Renal Dialysis |
| D016060 | Sorption Detoxification |
| D006440 | Hemofiltration |
| D005112 | Extracorporeal Circulation |
| D013514 | Surgical Procedures, Operative |
| D011175 | Positive-Pressure Respiration |