Geriatric Assessments in Elderly Diffuse Large B-cell Lymphoma

Multi-center, Prospective Cohort Study to Investigate the Impact of Comprehensive Geriatric Assessments on Survival and Toxicities in Elderly Diffuse Large B-cell Lymphoma Patients Treated With R-CHOP

This study investigate the impact of comprehensive geriatric assessments using activity of daily living (ADL), instrumental activity of daily living (IADL), and Charlson's comorbidity index (CCI) on survival and toxicities in Korean patients with diffuse large B-cell lymphoma (DLBCL) treated with R-CHOP.

Inclusion Criteria:

• Patients with newly diagnosed CD20+ DLBCL
• 65 years old or over
• Scheduled to receive R-CHOP chemotherapy
• Informed consent

Exclusion Criteria:

• Other histology than CD20+ DLBCL
• Primary central nervous system DLBCL
• Patients with a diagnosis of cancer (other than basal or squamous cell carcinoma of the skin, cervical carcinoma in situ, well differentiated thyroid cancer [papillary or follicular thyroid cancer]) within 3 years before the study entry or with any treatment for cancer within 3 years before entry
• Consent withdrawal