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Carbohydrate loading is an important component of enhanced recovery pathways. Preoperative carbohydrate treatments have been widely adopted as part of enhanced recovery after surgery (ERAS) or fast-track surgery protocols. Although fast-track surgery protocols have been widely investigated and have been shown to be associated with improved postoperative outcomes, some individual constituents of these protocols, including preoperative carbohydrate treatment, have not been subject to such robust analysis.To assess the effects of preoperative carbohydrate treatment, compared with placebo or preoperative fasting, on postoperative recovery and insulin resistance in adult patients undergoing elective surgery.
Patients received 400 mL of oral isotonic glucose (No NPO®, Daesang, Korea) 12 hours before anesthesia and 400 mL 2 hours before. CHL composition was standard: 12.5 g of carbohydrate per 100 mL, 12% monosaccharide, 12% disaccharide, 76% polysaccharide, 250 mOsm/kg and 50 kcal.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Allocated to MN NPO group, | Experimental |
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| Allocated to Placebo group | Placebo Comparator |
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| Allocated to Carbohydrated group | Active Comparator |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Allocated to Carbohydrated group | Dietary Supplement | Patients received 400 mL of oral isotonic glucose (No NPO®, Daesang, Korea) 12 hours before anesthesia and 400 mL 2 hours before. CHL composition was standard: 12.5 g of carbohydrate per 100 mL, 12% monosaccharide, 12% disaccharide, 76% polysaccharide, 250 mOsm/kg and 50 kcal. |
| Measure | Description | Time Frame |
|---|---|---|
| Quality of Recovery score using the QoR-40 Questionnaire | We check the QoR-40 Questionnaire at discharge day | We check the QoR-40 at POD1 after cholecystectomy , an expected average 3days |
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Inclusion Criteria:
Exclusion Criteria:
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| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 29915988 | Derived | Lee JS, Song Y, Kim JY, Park JS, Yoon DS. Effects of Preoperative Oral Carbohydrates on Quality of Recovery in Laparoscopic Cholecystectomy: A Randomized, Double Blind, Placebo-Controlled Trial. World J Surg. 2018 Oct;42(10):3150-3157. doi: 10.1007/s00268-018-4717-4. |
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| Allocated to Placebo group | Dietary Supplement | Patients received 400 mL of oral free water (Placebo) 12 hours before anesthesia and 400 mL 2 hours before. |
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| Allocated to MN NPO group, | Dietary Supplement | Patients received NPO from MN. |
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