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| ID | Type | Description | Link |
|---|---|---|---|
| 2012-A00904-39 | Other Identifier | ANSM |
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rate of inclusion too low
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The curative treatment and organ preservation in advanced squamous cell carcinoma of the oropharynx is multimodal. It involves induction chemotherapy and depending on the response radio-chemotherapy or surgery. The combination of these methods has important functional consequences.
The aim of this prospective pilot study is to describe swallowing, speech, but also patients' quality of life before and after therapeutic management (existing studies measuring these functions after treatment but not before).
This study will not change the patient's treatment. This will just be an evaluation, before any treatment, his ability to swallow, speak then, as in normal practice, after 3, 6 and 12 months after treatment.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Ability to swallow, speak and quality of life | This will just be an evaluation, before any treatment, his ability to swallow, speak and quality of life then, as in normal practice, after 3, 6 and 12 months after treatment. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Ability to swallow, speak and quality of life | Procedure | This study will not change the patient's treatment. This will just be an evaluation, before any treatment, his ability to swallow, speak, then his quality of life, as in normal practice, after 3, 6 and 12 months after treatment. |
| Measure | Description | Time Frame |
|---|---|---|
| change from swallowing disorder | A swallowing disorder will be determined by conducting a video-endoscopy and voluntary swallowing reflex (composite measure) | between day 0 and 1 year |
| Measure | Description | Time Frame |
|---|---|---|
| Change from phonation disorder | Phonation disorders will be evaluated by the scale "Voice Handicap Index" (composite measure) | between day 0 and 1 year |
| Change from quality of life | The quality of life will be assessed by the Quality of Life scale EORTC QLQ-C30 and QLC-HN35 (composite measure) |
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Inclusion Criteria:
Exclusion Criteria:
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Patietn with T3 or T4 stage squamous cell cancer of the oropharynx
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| Name | Affiliation | Role |
|---|---|---|
| Jean-Michel PRADES, MD PhD | CHU de SAINT-ETIENNE | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| CHu de SAINT-ETIENNE | Saint-Etienne | 42000 | France |
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| ID | Term |
|---|---|
| D000077195 | Squamous Cell Carcinoma of Head and Neck |
| D013060 | Speech |
| ID | Term |
|---|---|
| D002294 | Carcinoma, Squamous Cell |
| D002277 | Carcinoma |
| D009375 | Neoplasms, Glandular and Epithelial |
| D009370 | Neoplasms by Histologic Type |
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| ID | Term |
|---|---|
| D011788 | Quality of Life |
| ID | Term |
|---|---|
| D006304 | Health Status |
| D003710 | Demography |
| D015991 | Epidemiologic Measurements |
| D011634 | Public Health |
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|
| between day 0 and 1 year |
| D009369 | Neoplasms |
| D006258 | Head and Neck Neoplasms |
| D009371 | Neoplasms by Site |
| D014705 | Verbal Behavior |
| D003142 | Communication |
| D001519 | Behavior |
| D004778 |
| Environment and Public Health |