Port Wound Closure compares synthetic tissue adhesives with seam for cutaneous wound closure to port plant in terms of cosmetic results and time savings at comparable risk for wound infection.

Study patients who undergo a subcutaneous venous port implant procedure are randomized into control group (conventional sutures) or into interventional group (synthetic tissue adhesive). The intervention time is documented. Follow-up visit is performed 8 weeks after port implantation. It includes a photo documentation, quality of life questionnaire (EQ5D) and pain scala questionnaire (POSAS) by patient and by 3 independent observers as well as the documentation of complications.

Inclusion Criteria:

• Medical indication for port catheter implantation because of chemotherapy or parenteral nutrition

Exclusion Criteria:

• Children and adolescents < 18 years
• Thrombocytes < 50/nl
• PTT <50%
• INR >1.5
• Systemic or local infection of the interventional location
• Known allergy to used material
• Known allergy to Histoacryl, Cyanoacrylate, D&C Violett or Formaldehyd
• General contraindication of port catheter implantation