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| Name | Class |
|---|---|
| Erzincan University | OTHER |
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Infraclavicular block is one of the peripheral nerve block used in upper extremity surgery. Adjuvant agents are used in peripheral nerve blocks to increase the duration and block quality. We investigated that the effects of patient-controlled perineural dexmedetomidine application on postoperative analgesia.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| perineural bupivacaine | Active Comparator | patient-controlled infraclavicular perineural bupivacaine (1% bupivacaine (marcaine), 5 ml bolus dose, infusion rate of 5 ml / h, lockout time 1 hour) |
|
| perineural dexmedetomidine | Experimental | patient-controlled infraclavicular perineural dexmedetomidine (1% bupivacaine + 200 mic / 100cc dexmedetomidine, 5 ml bolus dose, infusion rate of 5 ml / h, lockout time 1 hour) |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Bupivacaine | Drug | patient- controlled infraclavicular perineural marcaine infusion |
|
| Measure | Description | Time Frame |
|---|---|---|
| visual analog scale | Scores range from 0 [no pain] to 10 [worst possible pain](streamdown:incomplete-link) | 3 month |
| Measure | Description | Time Frame |
|---|---|---|
| side effects | 3 month | |
| The effect of dexmedetomidine to the Ramsey Sedation Scale | 3 month |
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Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Erzincan Üniversity | Erzincan | Merkez | 24100 | Turkey (Türkiye) |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 19093908 | Background | Latifzai K, Sites BD, Koval KJ. Orthopaedic anesthesia - part 2. Common techniques of regional anesthesia in orthopaedics. Bull NYU Hosp Jt Dis. 2008;66(4):306-16. | |
| 20700680 | Background | Mariano ER, Loland VJ, Sandhu NS, Bishop ML, Lee DK, Schwartz AK, Girard PJ, Ferguson EJ, Ilfeld BM. Comparative efficacy of ultrasound-guided and stimulating popliteal-sciatic perineural catheters for postoperative analgesia. Can J Anaesth. 2010 Oct;57(10):919-26. doi: 10.1007/s12630-010-9364-7. Epub 2010 Aug 11. |
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| ID | Term |
|---|---|
| D002045 | Bupivacaine |
| D020927 | Dexmedetomidine |
| ID | Term |
|---|---|
| D000813 | Anilides |
| D000577 | Amides |
| D009930 | Organic Chemicals |
| D000814 | Aniline Compounds |
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| Dexmedetomidine | Drug | patient- controlled infraclavicular perineural marcaine with dexmedetomidine infusion |
|
| Background | Gray AT, Collins AB, Schafhalter-Zoppoth I. An introduction to femoral nerve and associated lumbar plexus nerve blocks under ultrasonic guidance. Tech Reg Ananesth Pain Man. 2004;8:155-63. |
| Background | Greengrass R, Steele S, Moretti G. Peripheral nerve blocks. In: Raj PP, editor. Textbook of regional anesthesia. New York: Churchill Livingstone; 2002. p. 325-77. |
| 14570643 | Background | White PF, Issioui T, Skrivanek GD, Early JS, Wakefield C. The use of a continuous popliteal sciatic nerve block after surgery involving the foot and ankle: does it improve the quality of recovery? Anesth Analg. 2003 Nov;97(5):1303-1309. doi: 10.1213/01.ANE.0000082242.84015.D4. |
| 11916811 | Background | di Benedetto P, Casati A, Bertini L, Fanelli G, Chelly JE. Postoperative analgesia with continuous sciatic nerve block after foot surgery: a prospective, randomized comparison between the popliteal and subgluteal approaches. Anesth Analg. 2002 Apr;94(4):996-1000, table of contents. doi: 10.1097/00000539-200204000-00041. |
| 22527409 | Result | Svediene S, Andrijauskas A, Ivaskevicius J, Saikus A. The efficacy comparison of on-demand boluses with and without basal infusion of 0.1 % bupivacaine via perineural femoral catheter after arthroscopic ACL reconstruction. Knee Surg Sports Traumatol Arthrosc. 2013 Mar;21(3):641-5. doi: 10.1007/s00167-012-1971-0. Epub 2012 Apr 13. |
| 24851163 | Result | Song JH, Shim HY, Lee TJ, Jung JK, Cha YD, Lee DI, Kim GW, Han JU. Comparison of dexmedetomidine and epinephrine as an adjuvant to 1% mepivacaine in brachial plexus block. Korean J Anesthesiol. 2014 Apr;66(4):283-9. doi: 10.4097/kjae.2014.66.4.283. Epub 2014 Apr 28. |
| D000588 |
| Amines |
| D007093 | Imidazoles |
| D001393 | Azoles |
| D006573 | Heterocyclic Compounds, 1-Ring |
| D006571 | Heterocyclic Compounds |