Analysis T Cells Response for Identification of Aspergillus Bronchitis With Cystic Fibrosis Patients

The study aims to asses the ability of cell tests based on the analysis of the anti-Aspergillus cell responses and identify Aspergillus bronchitis with patients with cystic fibrosis.

In addition, the study will evaluate the contribution of biological classification of aspergillosis according to criteria recently proposed by Baxter et al. compared to the classification used in clinical practice in the hospital of Montpellier.

Inclusion Criteria:

• Patient with cystic fibrosis followed at Resource Centers and Cystic Fibrosis Skills (CRCM) Montpellier
• Patient aged 15 or over
• Patient able to understand the nature, purpose and methodology of the study.
• Patient and his legal representative for minors who have given their free and informed consent
• Affiliate or beneficiary of a social security scheme.

Exclusion Criteria:

• Patients on antifungal treatment at the time of sampling
• Pregnant or breastfeeding
• Major protected by law (guardianship, curator or under Backup Justice)
• Inability to understand the nature and goals of the study and / or communication difficulties with the investigator
• Subject attending another search including a period of exclusion still going to run-in