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| ID | Type | Description | Link |
|---|---|---|---|
| 2012-A01182-41 | Other Identifier | ANSM |
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Nasal colonization with S. aureus is a risk factor for infection with this bacterium. A methodologically well conducted study of S. aureus bacteremia showed that 80% of S. aureus bacteremia with are due to the strain isolated in the nasal level. However, as part of a study coordinated by the CHU of Saint-Etienne, less than 50% of infections in prosthetic orthopedic devices have been linked to nasal carriage . Outside of exogenous infections, intestinal colonization with S. aureus could be an alternative source of endogenous infections with the waning of orthopedic surgery. In the general population, considering that about one third of the subjects were colonized with S. aureus nasal level and 1 in 5 in the intestine However the proportion of exclusive intestinal porting is not well known .
This study will analyze, among ICU patients, porting S. aureus nasal and rectal level. It will better clarify the relationship between nasal and rectal ports and the risk of developing an infection.
The adult patients hospitalized in intensive care at the University Hospital of Saint-Etienne have a multiresistant bacteria porting screening at the nose and rectum at admission and then once a week. These samples will be carried unchanged way for the study but will also be a research S Aureus
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Nasal and rectal samples | ICU patients with nasal and rectal bacterial samples for the presence of S Aureus |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Nasal and rectal bacterial samples | Procedure | Bacterial nasal and rectal samples at admission and one weekly for the presence of S Aureus |
|
| Measure | Description | Time Frame |
|---|---|---|
| prevalence of S. aureus colonization at rectal level | The presence of a colony of S. aureus on one of the samples | 1 month |
| Measure | Description | Time Frame |
|---|---|---|
| S. aureus strains similar to nasal and rectal level | S. aureus strains similar in molecular typing | 1 month |
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Inclusion Criteria:
Exclusion Criteria:
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Patients hospitalized in intensive care
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| Name | Affiliation | Role |
|---|---|---|
| Philippe BERTHELOT, Md-PhD | Centre Hospitalier Universitaire de Saint Etienne | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| CHU de Saint-Etienne | Saint-Etienne | 42000 | France |
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| ID | Term |
|---|---|
| D013203 | Staphylococcal Infections |
| ID | Term |
|---|---|
| D016908 | Gram-Positive Bacterial Infections |
| D001424 | Bacterial Infections |
| D001423 | Bacterial Infections and Mycoses |
| D007239 | Infections |
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bacterial samples