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| ID | Type | Description | Link |
|---|---|---|---|
| AD1501 | Other Identifier | Company Internal |
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The aim of this study is to understand the treatment patterns in patients with Pulmonary Arterial Hypertension (PAH) or Chronic Thromboembolic Pulmonary Hypertension (CTEPH) during a switch of treatment to Adempas in real-life clinical practice.
In addition, this study will describe patient demographics and reason for switching
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| BAY63-2521 | Patients who have been switched from a Pulmonary Hypertension treatment to Adempas |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Riociguat (Adempas, BAY63-2521) | Drug | As per the treating physicians discretion |
|
| Measure | Description | Time Frame |
|---|---|---|
| Starting Dose | Up to a total of 8 weeks of titration period | |
| Dose Increments | Up to a total of 8 weeks of titration period | |
| Final Dose | Up to a total of 8 weeks of titration period |
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Inclusion Criteria:
- Female and male adult patients diagnosed with PAH or inoperable/recurrent/persistent CTEPH who have been switched from a PH treatment (i.e. Endothelin Receptor Antagonist(ERAs), Phosphodiesterase-5 inhibitor(PDE5i) or Prostacyclin Analog (PCA) to Adempas
Exclusion Criteria:
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Source population of the study are patients with Pulmonary arterial hypertension(PAH) and Chronic thromboembolic pulmonary hypertension (CTEPH). Patients with this rare condition are mostly diagnosed and managed at specialist centers. This includes initiation or any change of Pulmonary Hypertension (PH) therapy. The participation of these specialized centers in the study is going to ensure the representativeness of the study population. In order to reduce selection bias physicians will be asked to include all eligible patients.
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| Name | Affiliation | Role |
|---|---|---|
| Bayer Study Director | Bayer | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Many Locations | Belgium | |||||
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| Many Locations |
| Canada |
| Many Locations | Colombia |
| Many Locations | Germany |
| Many Locations | Japan |
| Many Locations | Sweden |
| Many Locations | Turkey (Türkiye) |
| ID | Term |
|---|---|
| D006976 | Hypertension, Pulmonary |
| D000081029 | Pulmonary Arterial Hypertension |
| ID | Term |
|---|---|
| D008171 | Lung Diseases |
| D012140 | Respiratory Tract Diseases |
| D006973 | Hypertension |
| D014652 | Vascular Diseases |
| D002318 | Cardiovascular Diseases |
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| ID | Term |
|---|---|
| C542595 | riociguat |
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