CompletedInterventionalPhase 1Last updated Jul 24, 2017

Effect of Concomitant Use of an Antimycotic, an Antibiotic, a Spermicide or Tampons on Pharmacokinetics of Anastrozole and Levonorgestrel Released From Intra-vaginal Ring

A Parallel Group, Randomized, Open-label Study to Investigate the Effect of the Intravaginally Administered Antimycotic Miconazole, Antibiotic Clindamycin, Spermicide Nonoxynol-9, or Co-usage of Tampons on 3 Consecutive Days on the Pharmacokinetics of Anastrozole and Levonorgestrel Released From an Intra-vaginal Ring in Healthy Young Women

Overview

ClinicalTrials.gov ID: NCT02545452
Lead Sponsor: BayerINDUSTRY
Brief Summary: To investigate the pharmacokinetic effect of a vaginally administered antimycotic (miconazole), antibiotic (clindamycin), spermicide (nonoxynol-9) or the concomitant use of tampons during the use of an intravaginal ring releasing anastrozole and levonorgestrel
Study Type: Interventional

Status

Overall Status: Completed
Start Date: Sep 15, 2015Actual
Primary Completion Date: Mar 14, 2016Actual
Completion Date: Jul 29, 2016Actual

Study Record Dates

First Submitted: Sep 8, 2015
First Submitted that Met QC Criteria: Sep 9, 2015
First Posted: Sep 10, 2015Estimated
Last Update Submitted that Met QC Criteria: Jul 21, 2017
Last Update Posted: Jul 24, 2017Actual
Last Verified: Jul 2017

NCT04272008Completed

The Effects of Annovera™ and Tampon Co-Usage on the Pharmacokinetics of Segesterone Acetate and Ethinyl Estradiol

NCT02203331Completed

Bay98-7196, Dose Finding / POC Study

NCT02858024Completed

A Trial In Healthy HIV-Negative Women To Assess The Effect Of Menses And Tampon Use On The Pharmacokinetics Of Dapivirine, Delivered By Dapivirine Vaginal Ring-004, Containing 25 Mg Of Dapivirine

NCT00213096Completed

Effects of Hormonal Contraceptives on Liver Proteins and Coagulation Factors: A Comparison of a Contraceptive Vaginal Ring and an Oral Contraceptive

NCT02847286Completed

To Assess the Drug-drug Interaction Potential Between Dapivirine Vaginal Ring-004, Containing 25 mg of Dapivirine, and Clotrimazole 10 mg/g (1%)

NCT02451826Unknown status

A Study to Evaluate the Effect of a Contraceptive Vaginal Ring Delivering Ulipristal Acetate Combined With a Single or Repeated Levonorgestrel on Inhibition of Ovulation, Endometrial Changes and Bleeding Patterns in Normal Cycling Women