Not provided
Not provided
Not provided
| ID | Type | Description | Link |
|---|---|---|---|
| 2008-A00048-47 | Other Identifier | AFFSAPS |
Not provided
Not provided
Not provided
Inclusion rhythm too slow
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
In hemiplegic, there is very little data on the impact of neurological deficit on the microarchitecture independent of bone mineral density and composition of the bone marrow. Rare studies have shown the relationship between some micro-architectural parameters and severity of neurological deficit. There is no study in humans on the evolution of the parameters of the microarchitecture assessed by 3D micro-tomography in the early phase of the installation of neurological deficits after stroke, in terms of a bearing bone, tibia, that a non-load bearing bones, radius.
Each patient must answer several questionnaires about their calcium intake and its ability to perform everyday tasks. They will also have 3 blood samples (15 ml each time), 3 measure of bone by 3D micro-tomography and 2 MRI examination. These examinations and sampling will take place after 30 days after stroke onset (except for MRI) and again after three months and six months after the stroke (the same day as the medical follow-up visit).
Not provided
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Patients | Patients who have experienced a vascular hemiplegia and accept bone measure by MRI and 3D CT scan |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| MRI and 3D CT scan | Procedure | Measurement of bone microarchitecture at the legs and wrists by 3D CT Scan and measuring the proportion of fat in the imaging leg bone (MRI) |
|
| Measure | Description | Time Frame |
|---|---|---|
| Bone volume / tissue volume | Measure of Bone volume / tissue volume by the 3D CT scan | 90 days |
| Measure | Description | Time Frame |
|---|---|---|
| Bone volume / tissue volume | Measure of Bone volume / tissue volume by the 3D CT scan | 1 day |
| intraosseous fat | Measure the percentage of the intraosseous fat by MRI |
Not provided
Inclusion criteria
Exclusion criteria
Not provided
Not provided
Not provided
Patient aged at least 30 who have experienced a vascular hemiplegia within 30 days before enrollment
Not provided
| Name | Affiliation | Role |
|---|---|---|
| Thierry THOMAS, MD-PhD | Centre Hospitalier Universitaire de Saint Etienne | Principal Investigator |
Not provided
Not provided
| ID | Term |
|---|---|
| D020521 | Stroke |
| D006429 | Hemiplegia |
| ID | Term |
|---|---|
| D002561 | Cerebrovascular Disorders |
| D001927 | Brain Diseases |
| D002493 | Central Nervous System Diseases |
| D009422 | Nervous System Diseases |
Not provided
Not provided
| ID | Term |
|---|---|
| D009682 | Magnetic Resonance Spectroscopy |
| ID | Term |
|---|---|
| D013057 | Spectrum Analysis |
| D002623 | Chemistry Techniques, Analytical |
| D008919 | Investigative Techniques |
Not provided
Not provided
Not provided
Not provided
Not provided
blood sample
| 90 days |
| D014652 | Vascular Diseases |
| D002318 | Cardiovascular Diseases |
| D010243 | Paralysis |
| D009461 | Neurologic Manifestations |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |