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| ID | Type | Description | Link |
|---|---|---|---|
| 2014-A00650-47 | Registry Identifier | ID RCB |
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| Name | Class |
|---|---|
| La Région Basse-Normandie | OTHER |
| Université de Caen Normandie | OTHER |
| University Hospital, Caen | OTHER |
| Ecole Pratique des Hautes Etudes |
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Schemas describe mental structures storing recurrent and organized pattern of information. Schemas may have a strong influence on the process of storing and retrieving new information into memory. Previous approaches in the cognitive neuroscience of memory have entirely focused on the individual dimension of preexisting schemas. In the real world though, much of the researchers' experiences and knowledge are collective or shared. Such social-cultural frameworks stored in collective memory may also reshape and reconfigure the construction of individual memories. Attempting to ascertain the influence of collective schema on the neural substrates of individual memories using cutting-edge brain imaging methods represents the challenge that MULTIBRAIN2 seeks to tackle. To achieve this goal, the researchers will record brain activity during MRI scanning sessions in a group of 24 participants while they are performing an encoding followed by episodic memory retrieval tasks on pictures of the World War II Memorial of Caen. This study will seek to identify brain areas of the prefrontal cortex encoding the organization of knowledge in collective memory using multivariate analyses of brain activity patterns, and then to understand how such regions might modulate the recruitment of the hippocampus during episodic memory retrieval using analyses of effective connectivity. The organization of knowledge in collective memory is measured in parallel through 1) the analysis of French social memory of World War II using a corpus of thousand of television and radio shows from the National Institute of Audiovisual, and 2) an internet task measuring the organization of shared individual knowledge about World War II. Once collected, these data will help us to understand how collective schemas may shape the organization of individual memories.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Healthy participants | Experimental |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Episodic memory task | Behavioral |
| ||
| fMRI |
| Measure | Description | Time Frame |
|---|---|---|
| Blood Oxygen Level Dependent (BOLD) response as measured with fMRI | 1 hour |
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Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Fausto Viader, PUPH | University Hospital, Caen | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| GIP Cyceron | Caen | 14074 | France |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 31844272 | Result | Gagnepain P, Vallee T, Heiden S, Decorde M, Gauvain JL, Laurent A, Klein-Peschanski C, Viader F, Peschanski D, Eustache F. Collective memory shapes the organization of individual memories in the medial prefrontal cortex. Nat Hum Behav. 2020 Feb;4(2):189-200. doi: 10.1038/s41562-019-0779-z. Epub 2019 Dec 16. |
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| ID | Term |
|---|---|
| D008279 | Magnetic Resonance Imaging |
| ID | Term |
|---|---|
| D014054 | Tomography |
| D003952 | Diagnostic Imaging |
| D019937 | Diagnostic Techniques and Procedures |
| D003933 | Diagnosis |
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| OTHER |
| Equipement d'Excellence Matrice | OTHER |
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