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| Name | Class |
|---|---|
| Fondation de France | OTHER |
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Children with osteogenesis imperfecta are described as extremely sedentary and therefore fatigable, which strongly impacts their daily activities. The physical rehabilitation of these children is a fundamental aspect of treatment.
It has been shown that playing Wii console causes the same increase in energy expenditure than practicing moderate exercise, while ensuring user safety. This type of physical exercise with this type of fun game console might have a role in the treatment of OI children on the physical side but also on the psychological side.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| OI Children training with Nintendo Wii console | Experimental | Training for 3 months using the Nintendo Wii console on physical capacity in a group of children with Osteogenesis Imperfecta |
|
| Children with OI without training | No Intervention | No training |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Training with Nintendo Wii console | Other | Children with OI and draining for 3 months using Nintendo Wii console |
|
| Measure | Description | Time Frame |
|---|---|---|
| Change in physical capacity | Compare the change in physical capacity between training group of children with OI and control group of children with OI. The physical capacity is measured by maximal oxygen consumption VO2 max (ml/min/kg) measured during incremental exercise on cycle ergometer | from baseline to 3 months |
| Measure | Description | Time Frame |
|---|---|---|
| Change in physical capacity | Compare the change in physical capacity between training group of children with OI and control group of children with OI. The physical capacity is measured by maximal oxygen consumption VO2 max (ml/min/kg) measured during incremental exercise on cycle ergometer | From baseline to 9 months |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Vincent Gautheron, PhD | Centre Hospitalier Universitaire de Saint Etienne | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| CHU Saint-Etienne | Saint-Etienne | 42055 | France |
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| ID | Term |
|---|---|
| D010013 | Osteogenesis Imperfecta |
| ID | Term |
|---|---|
| D010009 | Osteochondrodysplasias |
| D001848 | Bone Diseases, Developmental |
| D001847 | Bone Diseases |
| D009140 | Musculoskeletal Diseases |
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| Compare physical inactivity between training group and control group |
Physical inactivity will be assessed by the Physical Activity Questionnaire (Q-APS) |
| Month 3 |
| Compare physical inactivity between training group and control group | Physical inactivity will be assessed by the Physical Activity Questionnaire (Q-APS) | Month 9 |
| Compare functional benefit between training group and control group | The functional benefit will be evaluated by the Functional Independence Measure (FIM) | Month 3 |
| Compare functional benefit between training group and control group | The functional benefit will be evaluated by the Functional Independence Measure (FIM) | Month 9 |
| Compare body fat between training group and control group | Body fat composition will be determined by skinfold measurements | Month 3 |
| Compare body fat between training group and control group | Body fat composition will be determined by skinfold measurements | Month 9 |
| Compare quality of life between training group and control group | The quality of life will be determined the Index Questionnaire Reintegration to Normal Life (IRVN) | Month 3 |
| Compare quality of life between training group and control group | The quality of life will be determined the Index Questionnaire Reintegration to Normal Life (IRVN) | Month 9 |
| Compare muscle strength between training group and control group | The muscle strength is a composite outcome. It will be assessed by:
| Month 3 |
| Compare muscle strength between training group and control group | The muscle strength is a composite outcome. It will be assessed by:
| Month 9 |
| Compare endurance of lower limbs between training group and control group | The endurance of the lower limbs will be measured by EMG analysis on incremental torque repetitive exercise | Month 3 |
| Compare endurance of lower limbs between training group and control group | The endurance of the lower limbs will be measured by EMG analysis on incremental torque repetitive exercise | Month 9 |
| Compare Energy expenditure of lower limbs between training group and control group | Energy expenditure is a composite outcome. It will be measured by collecting the respiratory exchange and heart rate during endurance, tennis and boxing games using the Nintendo WII | Month 3 |
| Compare Energy expenditure of lower limbs between training group and control group | Energy expenditure is a composite outcome. It will be measured by collecting the respiratory exchange and heart rate during endurance, tennis and boxing games using the Nintendo WII | Month 9 |
| Training tolerance | Reentrainment tolerance is a composite outcome. It will be assessed by :
| Baseline from 9 months |
| D030342 | Genetic Diseases, Inborn |
| D009358 | Congenital, Hereditary, and Neonatal Diseases and Abnormalities |
| D003095 | Collagen Diseases |
| D003240 | Connective Tissue Diseases |
| D017437 | Skin and Connective Tissue Diseases |