Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Facioscapulohumeral muscular dystrophy (FSHD) is the second most common muscular dystrophy with approximately 500 patients in Denmark. It is characterized by weakness and wasting of the facial muscles, the muscles in the shoulder region and of the legs.
The primary aim of this study is to investigate possible links and order between inflammation and fat infiltration in the muscles in patients with FSHD.
Approximately 15 patients with FSHD will be recruited for repeated MRI-scans during a year where the inflammation and fat infiltration in the muscles can be quantified.
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Patient group | Patients over 18 years old with confirmed FSHD (facioscapulohumeral muscular dystrophy). |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| No intervention, observational | Other |
|
| Measure | Description | Time Frame |
|---|---|---|
| Muscle inflammation | MRI (t2 mapping) will be used to quantify the inflammation in skeletal muscle. | One MRI scan per subject (exam lasts approximately 60 min.) |
| Muscle fat fraction | The Dixon MRI will be used to quantify the fat fraction in skeletal muscle. | One MRI scan per subject (exam lasts approximately 60 min.) |
| Measure | Description | Time Frame |
|---|---|---|
| Muscle strength | Isokinetic muscle dynamometry will be used to measure muscle strength. | One muscle strength test per subject (exam lasts approximately 60 min.) |
Not provided
Inclusion Criteria:
Exclusion Criteria:
Not provided
Not provided
Not provided
Persons in Denmark diagnosed with FSHD is invited to the study.
Not provided
Not provided
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Copenhagen Neuromuscular Center | Copenhagen | 2100 | Denmark |
Not provided
| ID | Term |
|---|---|
| C536391 | Facioscapulohumeral muscular dystrophy 1a |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided