Alcohol and Tobacco Consumption in Patients With Head and Neck or Lung Cancer : Interest of an Addiction Treatment

Alcohol and Tobacco Consumption in Patients With Head and Neck or Lung Cancer : Interest of Integrating the Addiction Treatment to the Initial Cancer Treatment Program

This is a multicenter, interventional, randomized study among patients with a first lung or head & neck cancer who are still active smokers ± alcohol misusers.The study will aim to compare the systematic implementation of an addiction treatment program initiated at hospital and integrated to the initial cancer treatment program (Arm A), versus the as-usual procedure, which consists in recommendations to follow an addiction treatment program (Arm B)

• Study proposal at the first medical consultation for therapeutic management of a first upper aerodigestive tract cancer or lung cancer.
• Selection criteria validation
• Collection of an informed consent
• Randomization :

Arm A: Experimental arm : Addiction consultation to the overall cancer treatment

Arm B: standard of care

The completion of questionnaires , the measurement of exhaled carbone monoxide rate using a CO tester for all patients, and the integrated addiction treatment among patients randomized in Arm A will not interfere with the medical treatment of cancer.

Inclusion Criteria:

• Patients with a first upper aerodigestive tract cancer or a lung cancer
• Initial cancer treatment
• Aged ≥ 18 and ≤65 years
• Living within a radius of 20 km from the CHRU de Lille/Oscar Lambret Center
• Patient with tobacco addiction: regular smoker = at least 7 cigarettes /week or 1 cigarette/day or short-term ex-smoker = regular smoker who has stopped smoking for less than 1 year from the inclusion date
• Performance status (ECOG/WHO) ≤ 2
• Registered with a social security system
• Informed and signed consent collected before initiation of any study procedures

Exclusion Criteria:

• Previous lung cancer or upper aerodigestive tract cancer
• Previous other cancer < 5 years, evoluting or treated at the inclusion (except uterine cervical carcinoma, basal cell or squamous cell skin carcinoma )
• Mesothelioma and esophageal cancer
• Occasional smoker (less than 7 cigarettes/week or less than 1 cigarette/day)
• Long-term ex-smokers who have stopped smoking for more than 1 year from the inclusion date
• Impossibility to comply with the study procedures due to geographic, social or mental reasons
• Patient under guardianship or tutorship
• Pregnant or breastfeeding women