Vaginally Administered Versus Per Oral Misoprostol in Induction of Labour

Vaginally Administered Versus Per Oral Misoprostol in Induction of Labour: a Randomized Trial

The purpose of this study is to investigate the effectiveness and safety of vaginally administered misoprostol (Misodel) versus per orally administered misoprostol (Cytotec) in induction of labour in nulliparous women.

Inclusion Criteria:

• Nulliparous
• Singleton at term pregnancy (>36+6 weeks)
• Unfavourable cervix (Bishop score < 6)
• Fetal cephalic position

Exclusion Criteria:

• Pre-term pregnancy (<37 weeks)
• Multiple pregnancy
• Rupture of membranes
• Other than fetal cephalic position
• Intra-uterine growth retardation
• Severe pre-eclampsia
• Severe hypertension
• Previous cesarean section