Allergy is a very common problem and can be a handicap in everyday life, specially when symptoms occur at work place. Some persons working with drosophila developed respiratory symptoms. Investigators tried to analyze if these manifestations could be due to a specific allergy to drosophila.

To do so, investigators invited laboratory workers who presented any symptoms in presence of drosophila to undergo skin prick tests in order to determine if a specific sensibilization to drosophila exists. Then, a blood sample is taken from these persons to research specific IgE directed against drosophila. By this way, investigators hope determine if a specific allergy to drosophila exists, its characteristics as prevalence, symptoms, populations concerned...in order to better protect laboratory workers and prevent allergy incidence.

Inclusion Criteria:

• major males or females (aged <68) who work in laboratory with drosophila in Montpellier (France)
• clinical symptoms in presence of drosophila
• The subject must be affiliated to a social security scheme
• Provision of informed consent prior to any study specific procedures

Exclusion Criteria:

• The patient has indicated against (or incompatible drug combination) concerning the implementation of a prick test
• antihistamine cure in progress
• Inability to understand the nature and goals of the study and / or communication difficulties with the investigator
• No affiliation to a French social security recipient or not such a scheme
• Major protected by law (guardianship, curator or under judicial protection)
• deprivation of liberty by judicial or administrative decision
• Increased likelihood of non compliance to the protocol or abandonment under study
• pregnancy or breastfeeding