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| Name | Class |
|---|---|
| Lakeshore Foundation | OTHER |
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This study will examine the effectiveness of two types of group exercise classes on the health and functional status in inactive adults age 18-65 with neurological conditions including Multiple Sclerosis, stroke, and spinal cord injury (SCI). Participants will be randomly assigned to one of three groups; Movement to Music, Adapted Yoga, or a waitlist group who will complete a home-based exercise intervention of either Movement to Music or Adapted Yoga.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Movement to Music | Experimental | The Movement to Music classes are composed of a set of exercises tailored to the specific needs and capabilities of each target group. The class will consist of and aerobic component and a strength component performed to varying music tempos. All movements will be choreographed by qualified dance instructors. |
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| Adapted Yoga | Active Comparator | Yoga classes will consist of postures adapted by qualified yoga instructors who have extensive experience in disability. |
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| Waitlist Control | No Intervention | This group will receive biweekly newsletters on a variety of topics. At the end of this trial, they will receive a home based intervention. |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Movement to Music | Behavioral |
| ||
| Adapted Yoga |
| Measure | Description | Time Frame |
|---|---|---|
| Cardiorespiratory Fitness as measured by sub-maximal VO2 | Submax VO2 is assessed by the six minute walk test or the six minute push test. Participants wear a portable metabolic cart while walking or pushing | 12 weeks |
| Pain as measured by PROMIS Pain Interference Short Form 8a | 12 weeks | |
| Fatigue as measured by PROMIS Fatigue Short Form 8a | 12 weeks | |
| Loneliness as measured by the Three-Item Loneliness Scale | 12 weeks | |
| Grip Strength as measured by hand grip dynamometer | 12 weeks | |
| Strength as measured by Biodex System 3 Multijoint dynamometer | Upper body strength is measured using a closed chain push/pull protocol. Lower body strength is measured using the knee flexion/extension protocol. | 12 weeks |
| Balance as measured by the Timed Up and Go | The Timed to Up and Go test is performed using a chair with arms. The participants stand up from the chair, walk to a mark measured three meters from the chair then return back to the seat. A score of greater than or equal to 14 seconds (average) has been shown to indicate a high risk of falling. | 12 weeks |
| Balance as measured by Biodex Limits of Stability | The Limits of Stability test is performed on the Biodex SD balance machine using the limits of stability protocol created by Biodex. |
| Measure | Description | Time Frame |
|---|---|---|
| Health Biomarkers as measured by blood analysis (insulin) | 12 weeks | |
| Health Biomarkers as measured by blood analysis (lipids) | 12 weeks | |
| Health Biomarkers as measured by blood analysis (fasting glucose) |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Lakeshore Foundation | Birmingham | Alabama | 35209 | United States |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 30092206 | Derived | Young HJ, Mehta TS, Herman C, Wang F, Rimmer JH. The Effects of M2M and Adapted Yoga on Physical and Psychosocial Outcomes in People With Multiple Sclerosis. Arch Phys Med Rehabil. 2019 Mar;100(3):391-400. doi: 10.1016/j.apmr.2018.06.032. Epub 2018 Aug 6. | |
| 29540164 | Derived | Rimmer JH, Herman C, Wingo B, Fontaine K, Mehta T. Methodological and clinical implications of a three-in-one Russian doll design for tracking health trajectories and improving health and function through innovative exercise treatments in adults with disability. BMC Med Res Methodol. 2018 Mar 14;18(1):28. doi: 10.1186/s12874-018-0480-3. |
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| ID | Term |
|---|---|
| D009103 | Multiple Sclerosis |
| D020521 | Stroke |
| ID | Term |
|---|---|
| D020278 | Demyelinating Autoimmune Diseases, CNS |
| D020274 | Autoimmune Diseases of the Nervous System |
| D009422 | Nervous System Diseases |
| D003711 | Demyelinating Diseases |
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| 12 weeks |
| Balance as measured by Repeated Chair Stands | The repeated chair stands test is performed by asking participants to stand up and sit down 5 times as fast as possible. A score of greater than or equal to 14 seconds (average) has been shown to indicate a high risk of falling. | 12 weeks |
| 12 weeks |
| Blood pressure | 12 weeks |
| Anthropometric measurements (weight) | 12 weeks |
| Circumference measurements to be reported as composite ratios (waist circumference, hip circumference, neck circumference) | 12 weeks |
| Physical Function with Mobility Aid as measured by PROMIS Physical Function with Mobility Aid 455b | 12 weeks |
| Anxiety as measured by PROMIS Emotional Distress-Anxiety Short Form 8a | 12 weeks |
| Depression as measured by PROMIS Emotional Distress-Depression Short Form 8a | 12 weeks |
| Sleep Disturbance as measured by PROMIS Sleep Disturbance Short Form 8a | 12 weeks |
| Ability to participate in social roles and activities as measured by PROMIS Ability to Participate in Social Roles and Activities Short Form 8a | 12 weeks |
| Nutrition Self-Efficacy as measured by the Nutrition Self-Efficacy Scale | 12 weeks |
| Physical Exercise Self-Efficacy as measured by the Physical Exercise Self Efficacy Scale | 12 weeks |
| PROMIS Pain Intensity Short Form | 12 Weeks |
| D001327 | Autoimmune Diseases |
| D007154 | Immune System Diseases |
| D002561 | Cerebrovascular Disorders |
| D001927 | Brain Diseases |
| D002493 | Central Nervous System Diseases |
| D014652 | Vascular Diseases |
| D002318 | Cardiovascular Diseases |