Omega-3 Supplementation for Smell Dysfunction

Effect of Omega-3 Supplementation in Patients With Smell Dysfunction Following Endoscopic Pituitary Tumor Resection

Omega-3 supplementation has been shown to have neuroprotective and potentially anti-inflammatory properties in both central and peripheral nerve injuries. The investigators are studying to see if omega-3 supplementation will affect olfactory (smell) function in patients with olfactory dysfunction following endoscopic removal of pituitary tumors.

Inclusion Criteria:

• sellar/parasellar tumor scheduled to undergo endoscopic transnasal transsphenoidal resection
• 18 years of age or older
• English speaking

Exclusion Criteria:

• Currently using blood thinning agents (aside from NSAIDs or cardioprotective ASA)
• elevated AST, ALT, or alk phos >10% outside of normal range, if randomized to omega-3 group
• diabetes, if randomized to omega-3 group and not already on omega-3 prescribed by another provider
• unable to provide informed consent due cognitive deficiencies