RCT Between UPP and Controls in Adult OSA

Randomized Control Trial Between Uvulopalatoplasty and Delayed Surgery (Controls)

To compare the effect of uvulopalatoplasty with no treatment in treating adult OSA.

Two arms: the intervention group undergo uvulopalatoplasty one month after baseline polysomnography (PSG1) and a PSG2 6 months after surgery .

The control group perform PSG 1 and are then waiting 6 months, thereafter undergo PSG2, then surgery and PSG3 6 months after surgery. All patients are followed for four years with PSG. Patients fill in questionnaires at PSG sessions, and blood pressure control the morning after.

Inclusion Criteria:

• AHI of 15 or more
• Friedmans stage I+II
• Tonsil size 0-1
• BMI<34
• ESS värde >7
• Failed treatment with CPAP and mandibular device

Exclusion Criteria:

• Severe cardiovascular or neurological disease
• ASA IV
• Not interested in surgical treatment