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Rapid infusion of blood is needed occasionally for control massive bleeding. For rapid infusion, external pressure can be used. The investigators will study correlation between external pressure and hemolysis and deformability of red blood cell.
Rapid infusion of blood is needed occasionally for control massive bleeding. For rapid infusion, external pressure can be used which cause hemolysis and alteration of red blood cell. The investigators will study correlation between variable external pressure and hemolysis and deformability of red blood cell. Differ from previous study, the investigator will use scanning electron microscope for observation red blood cell.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| 5days | Active Comparator | 5 days after blood sampling, various external pressure test will be done. Blood wil be stored in refrigerator(Celsius 4 degree) until study day. External pressure 0, 100, 150, 200, 250, 300mmHg will be applied to each blood sample. |
|
| 35days | Active Comparator | 35 days after blood sampling, various external pressure test will be done. Blood wil be stored in refrigerator(Celsius 4 degree) until study day. External pressure 0, 100, 150, 200, 250, 300mmHg will be applied to each blood sample. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Auto PC(Acemedical, Goyang-si, Korea) - 0mmHg(control) | Device | Blood pass through infusion set without external pressure. |
|
| Measure | Description | Time Frame |
|---|---|---|
| Hemolysis and alteration of deformability of red blood cell caused by external pressure | 1hour |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Hyub Huh, M.D. | Department of anesthesiology and pain medicine, Korea University Anam Hospital | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Korea university anam hospital | Seoul | 136705 | South Korea |
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| Auto PC(Acemedical, Goyang-si, Korea) - 150mmHg | Device | Blood pass through infusion set under external pressure (150mmHg) |
|
| Auto PC(Acemedical, Goyang-si, Korea) - 200mmHg | Device | Blood pass through infusion set under external pressure (200mmHg) |
|
| Auto PC(Acemedical, Goyang-si, Korea) - 250mmHg | Device | Blood pass through infusion set under external pressure (250mmHg) |
|
| Auto PC(Acemedical, Goyang-si, Korea) - 300mmHg | Device | Blood pass through infusion set under external pressure (300mmHg) |
|
| ID | Term |
|---|---|
| D006470 | Hemorrhage |
| ID | Term |
|---|---|
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
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