Carbon Dioxide Laser vs. Electrocoagulation for the Therapy of Condyloma

Carbon Dioxide Laser Ablation Versus Electrocoagulation - a Prospective, Randomized Single-center Trial Comparing Two Surgical Treatments in Women Undergoing Therapy for Condyloma Acuminata

In a randomized clinical trial of 114 women undergoing Treatment for condyloma acuminata, two surgical methods, the carbon dioxide laser Ablation and the excision by electrocoagulation, will be compared. The primary outcome of the study is the cosmetic result judged by the Patient 6 weeks after Treatment using a 11-step numerical rating scale (NRS), secondary outcomes are intervention time, operative complications, subjects and users satisfaction, postoperative pain and recurrence of genital warts.

Inclusion Criteria:

• informed consent
• women with anogenital affection of condyloma acuminata

Exclusion Criteria:

• significant language barrier
• pregnancy
• unwillingness to participate
• the use of blood thinner or known coagulation disorder
• the use of immunosuppressive medicament
• HIV-Infection
• malignant diseases
• local therapy within 8 weeks before Treatment
• wound healing disorder