Efficiency of Neurostimulation of Tibial Nerve in the Treatment of Low Anterior Resection Syndrome

Prospective and Randomized Study to Evaluate the Efficiency of Percutaneous Neurostimulation of Posterior Tibial Nerve in the Treatment of Low Anterior Resection Syndrome (LARS)

The aim of this study is to evaluate the efficiency of the Neuroestimulation of the Posterior Tibial Nerve for the treatment of this syndrome.

A multicentric, prospective, randomized study will be performed in patients affected with severe LARS symptoms. Patients will be randomized in two groups:

1. Control group- placebo
2. Treatment group: neuroestimulation of the posterior tibial nerve

Inclusion Criteria:

• Patients older than 18 and under 75 years who have been undergone anterior resection of the rectum with sphincter preservation for rectal cancer
• Patients with LARS score > 29

Exclusion Criteria:

• Patient with intestinal inflammatory disease
• Patients with known irritable colon disease
• Pregnancy patients
• Patients with others intestinal resection segments different from the rectum
• Patients with metastatic disease
• Patient with previous history of posterior tibial neurostimulation or sacral nerve stimulation