Prospective Trial of Autologous Platelet Rich Plasma in Aortic Surgery

Prospective Randomized Trial of Autologous Platelet Rich Plasma in Reducing Allogeneic Transfusions During Aortic Surgery Under Deep Hypothermic Circulatory Arrest

The purpose of this study is to determine whether autologous platelet rich plasma (APRP)is effective in reducing allogeneic blood transfusions during aortic surgery using deep hypothermic circulatory arrest.

Inclusion Criteria:

• patients undergoing elective or emergency aortic surgery using deep hypothermic circulatory arrest、
• preoperative platelet counts>150000000000/L、
• preoperative hematocrit>33%、
• without recent anticoagulants less than 5 days

Exclusion Criteria:

• preoperative coagulation disorder
• severe renal and liver dysfunction
• preoperative hemodynamic instability